Twenty-four AIDS patients with Toxoplasma encephalitis receiving cotrimoxazole and 5 receiving pyrimethamine plus clindamycin have been examined. Clinical and radiological response to treatment was evaluated and product limit method for survival data analysis was used. Eighteen out of 24 patients receiving cotrimoxazole and 3 out of 5 patients receiving clindamycin showed both clinical and radiological response. Cotrimoxazole was proven to be effective in treatment of Toxoplasma encephalitis and may represent an alternative to the choice therapy sulfadiazine-pyrimetamine. The actual efficacy of clindamycin has still to be evaluated.
|Translated title of the contribution||Therapeutic alternatives of toxoplasma encephalitis in AIDS patients: Cotrimoxazole and clindamycin|
|Number of pages||3|
|Journal||Giornale di Malattie Infettive e Parassitarie|
|Publication status||Published - 1991|
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