TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS: CONTRIMOSSAZOLO E CLINDAMICINA

Translated title of the contribution: Therapeutic alternatives of toxoplasma encephalitis in AIDS patients: Cotrimoxazole and clindamycin

V. Del Bono, A. Canessa, P. De Leo, N. Piersantelli, A. Terragna

Research output: Contribution to journalArticle

Abstract

Twenty-four AIDS patients with Toxoplasma encephalitis receiving cotrimoxazole and 5 receiving pyrimethamine plus clindamycin have been examined. Clinical and radiological response to treatment was evaluated and product limit method for survival data analysis was used. Eighteen out of 24 patients receiving cotrimoxazole and 3 out of 5 patients receiving clindamycin showed both clinical and radiological response. Cotrimoxazole was proven to be effective in treatment of Toxoplasma encephalitis and may represent an alternative to the choice therapy sulfadiazine-pyrimetamine. The actual efficacy of clindamycin has still to be evaluated.

Original languageItalian
Pages (from-to)989-991
Number of pages3
JournalGiornale di Malattie Infettive e Parassitarie
Volume43
Issue number11
Publication statusPublished - 1991

Fingerprint

Clindamycin
Sulfamethoxazole Drug Combination Trimethoprim
Toxoplasma
Encephalitis
Acquired Immunodeficiency Syndrome
Sulfadiazine
Pyrimethamine
Kaplan-Meier Estimate
Survival Analysis
Therapeutics

ASJC Scopus subject areas

  • Parasitology

Cite this

Del Bono, V., Canessa, A., De Leo, P., Piersantelli, N., & Terragna, A. (1991). TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS: CONTRIMOSSAZOLO E CLINDAMICINA. Giornale di Malattie Infettive e Parassitarie, 43(11), 989-991.

TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS : CONTRIMOSSAZOLO E CLINDAMICINA. / Del Bono, V.; Canessa, A.; De Leo, P.; Piersantelli, N.; Terragna, A.

In: Giornale di Malattie Infettive e Parassitarie, Vol. 43, No. 11, 1991, p. 989-991.

Research output: Contribution to journalArticle

Del Bono, V, Canessa, A, De Leo, P, Piersantelli, N & Terragna, A 1991, 'TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS: CONTRIMOSSAZOLO E CLINDAMICINA', Giornale di Malattie Infettive e Parassitarie, vol. 43, no. 11, pp. 989-991.
Del Bono, V. ; Canessa, A. ; De Leo, P. ; Piersantelli, N. ; Terragna, A. / TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS : CONTRIMOSSAZOLO E CLINDAMICINA. In: Giornale di Malattie Infettive e Parassitarie. 1991 ; Vol. 43, No. 11. pp. 989-991.
@article{757a258b475a4bc8b5889a3eb6db462c,
title = "TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS: CONTRIMOSSAZOLO E CLINDAMICINA",
abstract = "Twenty-four AIDS patients with Toxoplasma encephalitis receiving cotrimoxazole and 5 receiving pyrimethamine plus clindamycin have been examined. Clinical and radiological response to treatment was evaluated and product limit method for survival data analysis was used. Eighteen out of 24 patients receiving cotrimoxazole and 3 out of 5 patients receiving clindamycin showed both clinical and radiological response. Cotrimoxazole was proven to be effective in treatment of Toxoplasma encephalitis and may represent an alternative to the choice therapy sulfadiazine-pyrimetamine. The actual efficacy of clindamycin has still to be evaluated.",
author = "{Del Bono}, V. and A. Canessa and {De Leo}, P. and N. Piersantelli and A. Terragna",
year = "1991",
language = "Italian",
volume = "43",
pages = "989--991",
journal = "Giornale di Malattie Infettive e Parassitarie",
issn = "0017-0321",
publisher = "U T E T SpA",
number = "11",

}

TY - JOUR

T1 - TERAPIE ALTERNATIVE DELLA NEUROTOXOPLASMOSI IN AIDS

T2 - CONTRIMOSSAZOLO E CLINDAMICINA

AU - Del Bono, V.

AU - Canessa, A.

AU - De Leo, P.

AU - Piersantelli, N.

AU - Terragna, A.

PY - 1991

Y1 - 1991

N2 - Twenty-four AIDS patients with Toxoplasma encephalitis receiving cotrimoxazole and 5 receiving pyrimethamine plus clindamycin have been examined. Clinical and radiological response to treatment was evaluated and product limit method for survival data analysis was used. Eighteen out of 24 patients receiving cotrimoxazole and 3 out of 5 patients receiving clindamycin showed both clinical and radiological response. Cotrimoxazole was proven to be effective in treatment of Toxoplasma encephalitis and may represent an alternative to the choice therapy sulfadiazine-pyrimetamine. The actual efficacy of clindamycin has still to be evaluated.

AB - Twenty-four AIDS patients with Toxoplasma encephalitis receiving cotrimoxazole and 5 receiving pyrimethamine plus clindamycin have been examined. Clinical and radiological response to treatment was evaluated and product limit method for survival data analysis was used. Eighteen out of 24 patients receiving cotrimoxazole and 3 out of 5 patients receiving clindamycin showed both clinical and radiological response. Cotrimoxazole was proven to be effective in treatment of Toxoplasma encephalitis and may represent an alternative to the choice therapy sulfadiazine-pyrimetamine. The actual efficacy of clindamycin has still to be evaluated.

UR - http://www.scopus.com/inward/record.url?scp=0026319863&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026319863&partnerID=8YFLogxK

M3 - Articolo

AN - SCOPUS:0026319863

VL - 43

SP - 989

EP - 991

JO - Giornale di Malattie Infettive e Parassitarie

JF - Giornale di Malattie Infettive e Parassitarie

SN - 0017-0321

IS - 11

ER -