STRATEGIA TERAPEUTICA NEL DOLORE DA CANCRO

Translated title of the contribution: Therapeutic program in cancer pain

C. A. Pagni, A. Franzini

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Surgical and pharmacological management of cancer pain is described and discussed according to the physiopathological mechanisms underlying this complex syndrome. The therapeutic approach is planned in three major phases which may be employed alone or in combination, following an accurate evaluation of the pathophysiology and the clinical pattern in every single patient. The first phase includes multifocal pharmacological therapy by nonnarcotic drugs in order to affect, at different levels, the physiopathological mechanisms of cancer pain. The second phase is indicated when nonnarcotic drugs cannot achieve complete pain relief; neurosurgical procedures (nerve blocks, rhizotomies, cordotomies, etc.) are employed in this phase. The pharmacological treatment must be continued and associated with surgery. The third phase includes hypophysectomy, deep brain stimulation, psychosurgery and/or narcotic drug therapy, which are the last steps in the management of terminal cancer pain when all treatments have been ineffective. The results of this therapeutic program in 188 patients affected by pain of malignant origin are reported and discussed. 73 references are cited.

Original languageItalian
Pages (from-to)1-16
Number of pages16
JournalMinerva Medica
Volume72
Issue number1
Publication statusPublished - 1981

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Pharmacology
Cordotomy
Rhizotomy
Psychosurgery
Neurosurgical Procedures
Drug Therapy
Pain
Hypophysectomy
Deep Brain Stimulation
Nerve Block
Narcotics
Therapeutics
Cancer Pain
Pharmaceutical Preparations

ASJC Scopus subject areas

  • Medicine(all)

Cite this

STRATEGIA TERAPEUTICA NEL DOLORE DA CANCRO. / Pagni, C. A.; Franzini, A.

In: Minerva Medica, Vol. 72, No. 1, 1981, p. 1-16.

Research output: Contribution to journalArticle

Pagni, CA & Franzini, A 1981, 'STRATEGIA TERAPEUTICA NEL DOLORE DA CANCRO', Minerva Medica, vol. 72, no. 1, pp. 1-16.
Pagni, C. A. ; Franzini, A. / STRATEGIA TERAPEUTICA NEL DOLORE DA CANCRO. In: Minerva Medica. 1981 ; Vol. 72, No. 1. pp. 1-16.
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