Therapeutic strategies for pediatric non-alcoholic fatty liver disease

A challenge for health care providers [1]

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Non-alcoholic steato-hepatitis (NASH) is related to insulin resistance and, thus, frequently occurs as part of the metabolic changes that accompany obesity, diabetes and hyperlipidemia. In childhood, the overwhelming boost of obesity and its co-morbidities have lead to the extraordinarily increased prevalence of NASH. Establishing effective therapeutic strategies to treat the disease represents the challenge for hepatologists and gastroenterologists in the next decade. Therapeutic approaches have aimed at treating associated conditions (obesity, insulin resistance, hyperlipemia, etc) or reducing liver oxidative damage (vitamin E).

Original languageEnglish
Pages (from-to)2639-2641
Number of pages3
JournalWorld Journal of Gastroenterology
Volume13
Issue number18
Publication statusPublished - May 14 2007

Fingerprint

Health Personnel
Obesity
Pediatrics
Hyperlipidemias
Hepatitis
Insulin Resistance
Vitamin E
Therapeutics
Morbidity
Liver
Non-alcoholic Fatty Liver Disease
Gastroenterologists

Keywords

  • Insulin resistance
  • Non alcoholic steato-hepatitis
  • Non-alcoholic fatty liver disease
  • Thiazolidinediones
  • Vitamin E, diet

ASJC Scopus subject areas

  • Gastroenterology

Cite this

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abstract = "Non-alcoholic steato-hepatitis (NASH) is related to insulin resistance and, thus, frequently occurs as part of the metabolic changes that accompany obesity, diabetes and hyperlipidemia. In childhood, the overwhelming boost of obesity and its co-morbidities have lead to the extraordinarily increased prevalence of NASH. Establishing effective therapeutic strategies to treat the disease represents the challenge for hepatologists and gastroenterologists in the next decade. Therapeutic approaches have aimed at treating associated conditions (obesity, insulin resistance, hyperlipemia, etc) or reducing liver oxidative damage (vitamin E).",
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N2 - Non-alcoholic steato-hepatitis (NASH) is related to insulin resistance and, thus, frequently occurs as part of the metabolic changes that accompany obesity, diabetes and hyperlipidemia. In childhood, the overwhelming boost of obesity and its co-morbidities have lead to the extraordinarily increased prevalence of NASH. Establishing effective therapeutic strategies to treat the disease represents the challenge for hepatologists and gastroenterologists in the next decade. Therapeutic approaches have aimed at treating associated conditions (obesity, insulin resistance, hyperlipemia, etc) or reducing liver oxidative damage (vitamin E).

AB - Non-alcoholic steato-hepatitis (NASH) is related to insulin resistance and, thus, frequently occurs as part of the metabolic changes that accompany obesity, diabetes and hyperlipidemia. In childhood, the overwhelming boost of obesity and its co-morbidities have lead to the extraordinarily increased prevalence of NASH. Establishing effective therapeutic strategies to treat the disease represents the challenge for hepatologists and gastroenterologists in the next decade. Therapeutic approaches have aimed at treating associated conditions (obesity, insulin resistance, hyperlipemia, etc) or reducing liver oxidative damage (vitamin E).

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KW - Non-alcoholic fatty liver disease

KW - Thiazolidinediones

KW - Vitamin E, diet

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