Abstract
Background: Many papers have reported the results achieved with combined therapy for Ewing's tumors, but little is known about the treatment and outcome of those 30-40% of patients who relapse. Patients and methods: In a retrospective study, we evaluated 195 patients with Ewing's tumors treated at our institution from 1979 to 1997 with chemotherapy, radiotherapy, surgery or combined therapies after recurrence. Results: A second complete remission was achieved in only 26 patients (13.3%); 12 relapsed again and died of the tumor. The 5-year post-relapse event-free survival and overall survival were 9.7% and 13.8%, respectively; both of which were significantly better for patients who had relapsed ≥2 years after the beginning of the first treatment (14.3% versus 2.5%; P
Original language | English |
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Pages (from-to) | 1654-1659 |
Number of pages | 6 |
Journal | Annals of Oncology |
Volume | 14 |
Issue number | 11 |
DOIs | |
Publication status | Published - Nov 2003 |
Keywords
- Ewing's sarcoma
- Outcome
- Relapse
- Treatment
ASJC Scopus subject areas
- Cancer Research
- Oncology