La terapia con nasocannule ad alto flusso nel neonato pretermine.

Translated title of the contribution: [Therapy with high-flow nasal intubation in preterm infants].

F. Ciuffini, M. Colnaghi, A. Lavizzari, D. Mercadante, S. Musumeci, F. Mosca

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Despite of improved survival of premature infants, the incidence of long-term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV) is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP) is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC) is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby's face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS). It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.

Original languageItalian
Pages (from-to)118-124
Number of pages7
JournalPediatria Medica e Chirurgica
Volume35
Issue number3
Publication statusPublished - May 2013

Fingerprint

Nose
Intubation
Premature Infants
Noninvasive Ventilation
Therapeutics
Newborn Respiratory Distress Syndrome
Safety
Lung
Continuous Positive Airway Pressure
Lung Injury
Mechanics
Artificial Respiration
Ventilation
Mouth
Cannula
Nursing
Pressure
Incidence

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Surgery
  • Medicine(all)

Cite this

Ciuffini, F., Colnaghi, M., Lavizzari, A., Mercadante, D., Musumeci, S., & Mosca, F. (2013). La terapia con nasocannule ad alto flusso nel neonato pretermine. Pediatria Medica e Chirurgica, 35(3), 118-124.

La terapia con nasocannule ad alto flusso nel neonato pretermine. / Ciuffini, F.; Colnaghi, M.; Lavizzari, A.; Mercadante, D.; Musumeci, S.; Mosca, F.

In: Pediatria Medica e Chirurgica, Vol. 35, No. 3, 05.2013, p. 118-124.

Research output: Contribution to journalArticle

Ciuffini, F, Colnaghi, M, Lavizzari, A, Mercadante, D, Musumeci, S & Mosca, F 2013, 'La terapia con nasocannule ad alto flusso nel neonato pretermine.', Pediatria Medica e Chirurgica, vol. 35, no. 3, pp. 118-124.
Ciuffini F, Colnaghi M, Lavizzari A, Mercadante D, Musumeci S, Mosca F. La terapia con nasocannule ad alto flusso nel neonato pretermine. Pediatria Medica e Chirurgica. 2013 May;35(3):118-124.
Ciuffini, F. ; Colnaghi, M. ; Lavizzari, A. ; Mercadante, D. ; Musumeci, S. ; Mosca, F. / La terapia con nasocannule ad alto flusso nel neonato pretermine. In: Pediatria Medica e Chirurgica. 2013 ; Vol. 35, No. 3. pp. 118-124.
@article{a26070c383694a388ff700031c196885,
title = "La terapia con nasocannule ad alto flusso nel neonato pretermine.",
abstract = "Despite of improved survival of premature infants, the incidence of long-term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV) is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP) is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC) is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby's face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS). It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.",
author = "F. Ciuffini and M. Colnaghi and A. Lavizzari and D. Mercadante and S. Musumeci and F. Mosca",
year = "2013",
month = "5",
language = "Italian",
volume = "35",
pages = "118--124",
journal = "Pediatria Medica e Chirurgica",
issn = "0391-5387",
publisher = "Vicenza Pediatria Medica E Chirurgica",
number = "3",

}

TY - JOUR

T1 - La terapia con nasocannule ad alto flusso nel neonato pretermine.

AU - Ciuffini, F.

AU - Colnaghi, M.

AU - Lavizzari, A.

AU - Mercadante, D.

AU - Musumeci, S.

AU - Mosca, F.

PY - 2013/5

Y1 - 2013/5

N2 - Despite of improved survival of premature infants, the incidence of long-term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV) is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP) is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC) is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby's face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS). It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.

AB - Despite of improved survival of premature infants, the incidence of long-term pulmonary complications, mostly associated with ventilation-induced lung injury, remains high. Non invasive ventilation (NIV) is able to reduce the adverse effects of mechanical ventilation. Although nasal continuous positive airway pressure (NCPAP) is an effective mode of NIV, traumatic nasal complications and intolerance of the nasal interface are common. Recently high flow nasal cannula (HFNC) is emerging as an efficient, better tolerated form of NIV, allowing better access to the baby's face, which may improve nursing, feeding and bonding. The aim of this review is to discuss the available evidence of effectiveness and safety of HFNC in preterm newborns with respiratory distress syndrome (RDS). It is known that distending pressure generated by HFNC increases with increasing flow rate and decreasing infant size and varies according to the amount of leaks by nose and mouth. The effects of HFNC on lung mechanics, its clinical efficacy and safety are still insufficiently investigated. In conclusion, there is a growing evidence of the feasibility of HFNC as an alternative mode of NIV. However, further larger randomized trials are required, before being able to recommend HFNC in the treatment of moderate respiratory distress of preterm infants.

UR - http://www.scopus.com/inward/record.url?scp=84891712499&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84891712499&partnerID=8YFLogxK

M3 - Articolo

C2 - 23947111

AN - SCOPUS:84891712499

VL - 35

SP - 118

EP - 124

JO - Pediatria Medica e Chirurgica

JF - Pediatria Medica e Chirurgica

SN - 0391-5387

IS - 3

ER -