Thiamine Deficiency in a Developed Country: Acute Lactic Acidosis in Two Neonates Due to Unsupplemented Parenteral Nutrition

Guglielmo Salvatori, Vito Mondì, Fiammetta Piersigilli, Irma Capolupo, Veronica Pannone, Carlo Dionisi Vici, Cristiano Rizzo, Andrea Dotta

Research output: Contribution to journalArticle

Abstract

Thiamine is a water-soluble vitamin implicated in several metabolic processes. Its deficiency, due to prolonged parenteral nutrition without adequate vitamin supplementation, can lead to multiorgan failure characterized by cardiovascular impairment and metabolic acidosis refractory to bicarbonate administration. Only thiamine administration allows the remission of symptoms. We report 2 preterm infants with acute thiamine deficiency due to prolonged parenteral nutrition without adequate vitamin supplementation.

Original languageEnglish
Pages (from-to)886-889
Number of pages4
JournalJournal of Parenteral and Enteral Nutrition
Volume40
Issue number6
DOIs
Publication statusPublished - Aug 1 2016

Keywords

  • parenteral nutrition
  • preterm infant
  • shoshin beriberi
  • thiamine

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

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