TY - JOUR
T1 - Thin strut chrome-cobalt stent implantation for treatment of de-novo lesions in small coronary vessels
T2 - Results of the RISICO Italian Registry (Registro Italiano Mini VISION nei piccolo Vasi) utilizing the Mini VISION coronary stent platform
AU - Brambilla, Nedy
AU - Morici, Nuccia
AU - Bedogni, Francesco
AU - De Benedictis, Mauro
AU - Scrocca, Innocente
AU - Naldi, Monica
AU - Fiscella, Antonio
AU - Prosperi, Franco
AU - Dominici, Mauro
AU - Rebuzzi, Antonio
AU - Colombo, Antonio
AU - Sangiorgi, Giuseppe M.
PY - 2009/11
Y1 - 2009/11
N2 - Objectives: The Registro Italiano Mini VISION nei piccoli Vasi registry is a prospective, multicenter, observational study, aimed at assessing immediate and long-term angiographic and clinical outcomes of a small-vessel cobalt-chrome super alloy-dedicated stent (Multi-Link RX VISION) in de-novo and long lesions. Background: Small artery size is an important determinant of poor outcomes in percutaneous coronary interventions. Methods: Patients with ischemic heart disease were included. The primary end point was procedural success. Secondary end points included clinical restenosis (need for target lesion revascularization ), incidence of major adverse cardiac events at 6 months, and cost-effectiveness analysis. Results: Between September 2004 and October 2005, 143 patients (mean age 67 ± 11 years; 22% diabetes) were enrolled; 6-month follow-up was completed in May 2006. Average lesion length, mean stent length and diameter were 16.8 ± 7.1, 17.01 ± 3.9 and 2.41 ± 0.14 mm, respectively. Procedural success was 96%. At 6-month follow-up, the hierarchical major adverse cardiac event rate was 11.6%, 2.9% deaths, 2.9% myocardial infarction and 5.8% target lesion revascularization. Cost-effectiveness analysis will be reported in a further publication. Conclusion: Small-vessel disease treatment with Mini VISION stents permits an elevated procedural success rate with low incidence of clinical restenosis and major adverse cardiac events at mid-term follow-up. Such results require confirmation by means of a randomized controlled study against drug-eluting stents.
AB - Objectives: The Registro Italiano Mini VISION nei piccoli Vasi registry is a prospective, multicenter, observational study, aimed at assessing immediate and long-term angiographic and clinical outcomes of a small-vessel cobalt-chrome super alloy-dedicated stent (Multi-Link RX VISION) in de-novo and long lesions. Background: Small artery size is an important determinant of poor outcomes in percutaneous coronary interventions. Methods: Patients with ischemic heart disease were included. The primary end point was procedural success. Secondary end points included clinical restenosis (need for target lesion revascularization ), incidence of major adverse cardiac events at 6 months, and cost-effectiveness analysis. Results: Between September 2004 and October 2005, 143 patients (mean age 67 ± 11 years; 22% diabetes) were enrolled; 6-month follow-up was completed in May 2006. Average lesion length, mean stent length and diameter were 16.8 ± 7.1, 17.01 ± 3.9 and 2.41 ± 0.14 mm, respectively. Procedural success was 96%. At 6-month follow-up, the hierarchical major adverse cardiac event rate was 11.6%, 2.9% deaths, 2.9% myocardial infarction and 5.8% target lesion revascularization. Cost-effectiveness analysis will be reported in a further publication. Conclusion: Small-vessel disease treatment with Mini VISION stents permits an elevated procedural success rate with low incidence of clinical restenosis and major adverse cardiac events at mid-term follow-up. Such results require confirmation by means of a randomized controlled study against drug-eluting stents.
KW - Bare metal stent
KW - Percutaneous coronary intervention
KW - Small coronary vessels
UR - http://www.scopus.com/inward/record.url?scp=70349817078&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=70349817078&partnerID=8YFLogxK
U2 - 10.2459/JCM.0b013e32832e6446
DO - 10.2459/JCM.0b013e32832e6446
M3 - Article
C2 - 19550353
AN - SCOPUS:70349817078
VL - 10
SP - 852
EP - 858
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 11
ER -