Thoracoscopic thymectomy in autoimmune myasthenia: Results of left-sided approach

Tommaso C. Mineo, Eugenio Pompeo, Toni E. Lerut, Giorgio Bernardi, Willy Coosemans, Italo Nofroni

Research output: Contribution to journalArticlepeer-review


Background. We undertook to analyze the results of video-assisted thoracoscopic thymectomy through a left-sided approach in patients with autoimmune myasthenia. Methods. Between 1993 and 1997, 31 patients underwent thoracoscopic thymectomy by a uniform left-sided approach. There were 8 men and 23 women with a mean age of 34 ± 12 years. Results. Preoperative duration of disease was 14.8 ± 11 months. There were no operative deaths or major complications. The mean hospital stay was 5.2 ± 2.8 days. Mean follow- up was 39.6 ± 15 months and was 100% complete. At 48 months, remission and improvement rates were 36% and 96%, respectively. Shorter duration of symptoms (<12 months) correlated with improved outcome (13 of 13 patients versus 10 of 14 patients; p = 0.036). Age, sex, Osserman class, corticosteroid therapy, presence of ectopic thymic tissue, and temporary postoperative symptom increase (deterioration) did not affect outcome. Conclusions. Thoracoscopic thymectomy facilitated the goal of early thymectomy. Through a left-sided approach, improvement or remission was achieved in more than 95% of the patients. Thoracoscopic thymectomy should be considered a valid less invasive alternative to the most radical open approaches. (C) 2000 The Society of Thoracic Surgeons.

Original languageEnglish
Pages (from-to)1537-1541
Number of pages5
JournalAnnals of Thoracic Surgery
Issue number5
Publication statusPublished - May 2000

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery


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