Three cases of Zika virus imported in Italy: Need for a clinical awareness and evidence-based knowledge

Research output: Contribution to journalArticle

Abstract

Background: Since early 2015, a large epidemic of Zika Virus (ZIKV) is spreading across South and Central America. An association between congenital neurological malformations (mainly microcephaly), other neurological manifestations such as Guillain-Barrè Syndrome, and ZIKV infection is suspected. Case presentation: Three confirmed cases of ZIKV in travelers returning from Brazil between May 2015 and January 2016 are described. All patients had mild symptoms with no neurological complications. Conclusions: An increasing awareness among clinicians about this emerging disease is advisable, both for the need to provide correct additional information to the patients and to travelers, with a special focus on pregnant women, and for the presence of the competent vector in Southern Europe.

Original languageEnglish
Article number669
JournalBMC Infectious Diseases
Volume16
Issue number1
DOIs
Publication statusPublished - Nov 11 2016

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Italy
Central America
Microcephaly
South America
Neurologic Manifestations
Brazil
Pregnant Women
Zika Virus
Zika Virus Infection

Keywords

  • Emerging or re-emerging diseases
  • Imported viral diseases
  • Pregnancy
  • Surveillance
  • Travel
  • Zika virus

ASJC Scopus subject areas

  • Infectious Diseases

Cite this

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title = "Three cases of Zika virus imported in Italy: Need for a clinical awareness and evidence-based knowledge",
abstract = "Background: Since early 2015, a large epidemic of Zika Virus (ZIKV) is spreading across South and Central America. An association between congenital neurological malformations (mainly microcephaly), other neurological manifestations such as Guillain-Barr{\`e} Syndrome, and ZIKV infection is suspected. Case presentation: Three confirmed cases of ZIKV in travelers returning from Brazil between May 2015 and January 2016 are described. All patients had mild symptoms with no neurological complications. Conclusions: An increasing awareness among clinicians about this emerging disease is advisable, both for the need to provide correct additional information to the patients and to travelers, with a special focus on pregnant women, and for the presence of the competent vector in Southern Europe.",
keywords = "Emerging or re-emerging diseases, Imported viral diseases, Pregnancy, Surveillance, Travel, Zika virus",
author = "Emanuele Nicastri and Raffaella Pisapia and Angela Corpolongo and Fusco, {Francesco Maria} and Stefania Cicalini and Paola Scognamiglio and Concetta Castilletti and Licia Bordi and {Di Caro}, Antonino and Capobianchi, {Maria Rosaria} and Vincenzo Puro and Giuseppe Ippolito",
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language = "English",
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T1 - Three cases of Zika virus imported in Italy

T2 - Need for a clinical awareness and evidence-based knowledge

AU - Nicastri, Emanuele

AU - Pisapia, Raffaella

AU - Corpolongo, Angela

AU - Fusco, Francesco Maria

AU - Cicalini, Stefania

AU - Scognamiglio, Paola

AU - Castilletti, Concetta

AU - Bordi, Licia

AU - Di Caro, Antonino

AU - Capobianchi, Maria Rosaria

AU - Puro, Vincenzo

AU - Ippolito, Giuseppe

PY - 2016/11/11

Y1 - 2016/11/11

N2 - Background: Since early 2015, a large epidemic of Zika Virus (ZIKV) is spreading across South and Central America. An association between congenital neurological malformations (mainly microcephaly), other neurological manifestations such as Guillain-Barrè Syndrome, and ZIKV infection is suspected. Case presentation: Three confirmed cases of ZIKV in travelers returning from Brazil between May 2015 and January 2016 are described. All patients had mild symptoms with no neurological complications. Conclusions: An increasing awareness among clinicians about this emerging disease is advisable, both for the need to provide correct additional information to the patients and to travelers, with a special focus on pregnant women, and for the presence of the competent vector in Southern Europe.

AB - Background: Since early 2015, a large epidemic of Zika Virus (ZIKV) is spreading across South and Central America. An association between congenital neurological malformations (mainly microcephaly), other neurological manifestations such as Guillain-Barrè Syndrome, and ZIKV infection is suspected. Case presentation: Three confirmed cases of ZIKV in travelers returning from Brazil between May 2015 and January 2016 are described. All patients had mild symptoms with no neurological complications. Conclusions: An increasing awareness among clinicians about this emerging disease is advisable, both for the need to provide correct additional information to the patients and to travelers, with a special focus on pregnant women, and for the presence of the competent vector in Southern Europe.

KW - Emerging or re-emerging diseases

KW - Imported viral diseases

KW - Pregnancy

KW - Surveillance

KW - Travel

KW - Zika virus

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