Three-dimensional analysis of pulmonary nodules

Variability of semiautomated volume measurements between different versions of the same software

M. F. Rinaldi, T. Bartalena, L. Braccaioli, N. Sverzellati, S. Mattioli, E. Rimondi, G. Rossi, M. Zompatori, G. Battista, R. Canini

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Purpose. This study was done to evaluate the variability of semiautomated volume measurements of solid pulmonary nodules between two different versions of the same volumetric software. Materials and methods. The volumes of 100 solid intraparenchymal nodules (mean volume 88.10 mm 3; range 7.36-595.25 mm 3) studied with the same multidetector computed tomography (MDCT) protocol were determined using two different versions of the same volumetric software (LungCARE 2006G and LungCARE 2007S). The 2006G version is based on a single-segmentation algorithm, whereas the newer version features two algorithms: SmallSizeNodule and AllSizeNodule. The results obtained with the 2006G version were compared with those of the 2007S version with the SmallSizeNodule algorithm, as recommended by the user manual. In addition, we compared the volumetric measurements obtained by the two different algorithms of the 2007S version. Results. The 2006G version and the 2007S version with the SmallSizeNodule algorithm agreed in only two of 100 cases and showed a mean variability of 1.66% (range 0%-8.78%). A more significant volumetric discrepancy was observed between the two different algorithms of the 2007S version, with the AllSizeNodule algorithm providing on average larger volumes (mean variability 71.08%; range 6.02%-218.80%) than SmallSizeNodule. Volume discrepancies were more pronounced in the subgroups of smaller nodules in all comparisons. Conclusions. There is variability also in the results provided by different versions of the same volumetric software, and this may affect the calculation of the noduledoubling time. Computer-aided assessment of the growth of lung nodules should always be performed using the same version of volumetric software and the same segmentation algorithm.

Original languageEnglish
Pages (from-to)403-412
Number of pages10
JournalRadiologia Medica
Volume115
Issue number3
DOIs
Publication statusPublished - Apr 2010

Fingerprint

Software
Lung
Multidetector Computed Tomography
Growth

Keywords

  • 3D volumetry
  • Multidetector CT
  • Pulmonary nodule

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Three-dimensional analysis of pulmonary nodules : Variability of semiautomated volume measurements between different versions of the same software. / Rinaldi, M. F.; Bartalena, T.; Braccaioli, L.; Sverzellati, N.; Mattioli, S.; Rimondi, E.; Rossi, G.; Zompatori, M.; Battista, G.; Canini, R.

In: Radiologia Medica, Vol. 115, No. 3, 04.2010, p. 403-412.

Research output: Contribution to journalArticle

Rinaldi, MF, Bartalena, T, Braccaioli, L, Sverzellati, N, Mattioli, S, Rimondi, E, Rossi, G, Zompatori, M, Battista, G & Canini, R 2010, 'Three-dimensional analysis of pulmonary nodules: Variability of semiautomated volume measurements between different versions of the same software', Radiologia Medica, vol. 115, no. 3, pp. 403-412. https://doi.org/10.1007/s11547-010-0511-6
Rinaldi, M. F. ; Bartalena, T. ; Braccaioli, L. ; Sverzellati, N. ; Mattioli, S. ; Rimondi, E. ; Rossi, G. ; Zompatori, M. ; Battista, G. ; Canini, R. / Three-dimensional analysis of pulmonary nodules : Variability of semiautomated volume measurements between different versions of the same software. In: Radiologia Medica. 2010 ; Vol. 115, No. 3. pp. 403-412.
@article{6e3f6e5f409d4c6899db6c79e32596a0,
title = "Three-dimensional analysis of pulmonary nodules: Variability of semiautomated volume measurements between different versions of the same software",
abstract = "Purpose. This study was done to evaluate the variability of semiautomated volume measurements of solid pulmonary nodules between two different versions of the same volumetric software. Materials and methods. The volumes of 100 solid intraparenchymal nodules (mean volume 88.10 mm 3; range 7.36-595.25 mm 3) studied with the same multidetector computed tomography (MDCT) protocol were determined using two different versions of the same volumetric software (LungCARE 2006G and LungCARE 2007S). The 2006G version is based on a single-segmentation algorithm, whereas the newer version features two algorithms: SmallSizeNodule and AllSizeNodule. The results obtained with the 2006G version were compared with those of the 2007S version with the SmallSizeNodule algorithm, as recommended by the user manual. In addition, we compared the volumetric measurements obtained by the two different algorithms of the 2007S version. Results. The 2006G version and the 2007S version with the SmallSizeNodule algorithm agreed in only two of 100 cases and showed a mean variability of 1.66{\%} (range 0{\%}-8.78{\%}). A more significant volumetric discrepancy was observed between the two different algorithms of the 2007S version, with the AllSizeNodule algorithm providing on average larger volumes (mean variability 71.08{\%}; range 6.02{\%}-218.80{\%}) than SmallSizeNodule. Volume discrepancies were more pronounced in the subgroups of smaller nodules in all comparisons. Conclusions. There is variability also in the results provided by different versions of the same volumetric software, and this may affect the calculation of the noduledoubling time. Computer-aided assessment of the growth of lung nodules should always be performed using the same version of volumetric software and the same segmentation algorithm.",
keywords = "3D volumetry, Multidetector CT, Pulmonary nodule",
author = "Rinaldi, {M. F.} and T. Bartalena and L. Braccaioli and N. Sverzellati and S. Mattioli and E. Rimondi and G. Rossi and M. Zompatori and G. Battista and R. Canini",
year = "2010",
month = "4",
doi = "10.1007/s11547-010-0511-6",
language = "English",
volume = "115",
pages = "403--412",
journal = "Radiologia Medica",
issn = "0033-8362",
publisher = "Springer-Verlag Italia s.r.l.",
number = "3",

}

TY - JOUR

T1 - Three-dimensional analysis of pulmonary nodules

T2 - Variability of semiautomated volume measurements between different versions of the same software

AU - Rinaldi, M. F.

AU - Bartalena, T.

AU - Braccaioli, L.

AU - Sverzellati, N.

AU - Mattioli, S.

AU - Rimondi, E.

AU - Rossi, G.

AU - Zompatori, M.

AU - Battista, G.

AU - Canini, R.

PY - 2010/4

Y1 - 2010/4

N2 - Purpose. This study was done to evaluate the variability of semiautomated volume measurements of solid pulmonary nodules between two different versions of the same volumetric software. Materials and methods. The volumes of 100 solid intraparenchymal nodules (mean volume 88.10 mm 3; range 7.36-595.25 mm 3) studied with the same multidetector computed tomography (MDCT) protocol were determined using two different versions of the same volumetric software (LungCARE 2006G and LungCARE 2007S). The 2006G version is based on a single-segmentation algorithm, whereas the newer version features two algorithms: SmallSizeNodule and AllSizeNodule. The results obtained with the 2006G version were compared with those of the 2007S version with the SmallSizeNodule algorithm, as recommended by the user manual. In addition, we compared the volumetric measurements obtained by the two different algorithms of the 2007S version. Results. The 2006G version and the 2007S version with the SmallSizeNodule algorithm agreed in only two of 100 cases and showed a mean variability of 1.66% (range 0%-8.78%). A more significant volumetric discrepancy was observed between the two different algorithms of the 2007S version, with the AllSizeNodule algorithm providing on average larger volumes (mean variability 71.08%; range 6.02%-218.80%) than SmallSizeNodule. Volume discrepancies were more pronounced in the subgroups of smaller nodules in all comparisons. Conclusions. There is variability also in the results provided by different versions of the same volumetric software, and this may affect the calculation of the noduledoubling time. Computer-aided assessment of the growth of lung nodules should always be performed using the same version of volumetric software and the same segmentation algorithm.

AB - Purpose. This study was done to evaluate the variability of semiautomated volume measurements of solid pulmonary nodules between two different versions of the same volumetric software. Materials and methods. The volumes of 100 solid intraparenchymal nodules (mean volume 88.10 mm 3; range 7.36-595.25 mm 3) studied with the same multidetector computed tomography (MDCT) protocol were determined using two different versions of the same volumetric software (LungCARE 2006G and LungCARE 2007S). The 2006G version is based on a single-segmentation algorithm, whereas the newer version features two algorithms: SmallSizeNodule and AllSizeNodule. The results obtained with the 2006G version were compared with those of the 2007S version with the SmallSizeNodule algorithm, as recommended by the user manual. In addition, we compared the volumetric measurements obtained by the two different algorithms of the 2007S version. Results. The 2006G version and the 2007S version with the SmallSizeNodule algorithm agreed in only two of 100 cases and showed a mean variability of 1.66% (range 0%-8.78%). A more significant volumetric discrepancy was observed between the two different algorithms of the 2007S version, with the AllSizeNodule algorithm providing on average larger volumes (mean variability 71.08%; range 6.02%-218.80%) than SmallSizeNodule. Volume discrepancies were more pronounced in the subgroups of smaller nodules in all comparisons. Conclusions. There is variability also in the results provided by different versions of the same volumetric software, and this may affect the calculation of the noduledoubling time. Computer-aided assessment of the growth of lung nodules should always be performed using the same version of volumetric software and the same segmentation algorithm.

KW - 3D volumetry

KW - Multidetector CT

KW - Pulmonary nodule

UR - http://www.scopus.com/inward/record.url?scp=77953233890&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77953233890&partnerID=8YFLogxK

U2 - 10.1007/s11547-010-0511-6

DO - 10.1007/s11547-010-0511-6

M3 - Article

VL - 115

SP - 403

EP - 412

JO - Radiologia Medica

JF - Radiologia Medica

SN - 0033-8362

IS - 3

ER -