Three-dimensional display of myocardial perfusion detection of ischemic lesions using a new image subtraction method

Pier Paolo Ferretti, Giovanni Borasi, Diana Salvo, Desiderio Serafini, Annibale Versari

Research output: Contribution to journalArticle

Abstract

A recent, commercially available computer program for the three-dimensional (3D) display of single-photon emission tomography (SPET) data was used to study myocardial perfusion in patients with coronary artery disease (CAD). To enable the detection of small ischemic lesions, the authors proposed a new "distance-subtraction" method: after suitable centering of the axial slices, 3D "distance-shaded" images of the stress study were subtracted from the corresponding views of the rest study. With this technique, small changes in surface-to-observer distance were highlighted, thus enabling us to detect nontransmural ischemic areas of the myocardium. General characteristics and possibilities of the subtraction technique were tested on a simple myocardial phantom. Some clinical results of the application of this method on CAD patients are presented and discussed. In CAD patients in whom only nontransmural ischemic lesions are present, the subtraction of "distance-shaded" images is decisive for a correct diagnosis.

Original languageEnglish
Pages (from-to)55-60
Number of pages6
JournalEuropean Journal Of Nuclear Medicine
Volume17
Issue number1-2
DOIs
Publication statusPublished - Jan 1990

Keywords

  • Heart
  • Myocardial perfusion
  • Three-dimensional display
  • Three-dimensional subtraction

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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