Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings

L. M. Sconfienza, F. Lacelli, V. Caldiera, N. Perrone, F. Piscopo, N. Gandolfo, G. Serafini

Research output: Contribution to journalArticle

Abstract

Introduction: To compare the diagnostic values of three-dimensional sonohysterography (3DSH), transvaginal ultrasound (TVUS), and 2-dimensional sonohysterography (2DSH) in the work-up of abnormal uterine bleeding (AUB), in particular the ability of each method to identify intracavitary lesions arising from the endometrium or uterine wall. Materials and methods: 24 patients referred for AUB underwent TVUS followed by 2-D and 3-D HS in the same session. Three-dimensional data were acquired with a free-hand technique during maximal distention of the uterus. Within 10 days of the sonographic session, each patient underwent hysteroscopy, which was considered the reference standard. For each of the 3 imaging methods, we calculated sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy. Results: Hysteroscopy demonstrated the presence of an intrauterine lesion in 21/24 patients (87.5%). In 3/24 patients hysteroscopy was negative. For TVUS, 2DSH, and 3DSH, sensitivity was 76% (16/21), 90% (19/21), 100% (21/21), respectively; specificity was 100% (3/3), 100% (19/19), 100% (21/21); PPV was 100%, 100%, 100%; NPV was 37%, 60%, 100%; accuracy was 76%, 90%, 100%. Conclusions: 3DSH is more sensitive that 2DSH or TVUS in the detection of intrauterine lesions. If these preliminary results are confirmed in larger studies, 3DSH could be proposed as a valuable alternative to diagnostic hysteroscopy.

Original languageEnglish
Pages (from-to)16-21
Number of pages6
JournalJournal of Ultrasound
Volume13
Issue number1
DOIs
Publication statusPublished - Mar 2010

Keywords

  • Abnormal uterine bleeding
  • Hysteroscopy
  • Sonohysterography
  • Three-dimensional sonohysterography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Internal Medicine

Fingerprint Dive into the research topics of 'Three-dimensional sonohysterography for examination of the uterine cavity in women with abnormal uterine bleeding: Preliminary findings'. Together they form a unique fingerprint.

  • Cite this