Three dimensional spectral domain optical coherence tomography features of retinal-choroidal anastomosis

Giuseppe Querques, Fernando O. Avellis, Lea Querques, Nathalie Massamba, Francesco Bandello, Eric H. Souied

Research output: Contribution to journalArticlepeer-review

Abstract

Background To correlate the three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) features of retinal-choroidal anastomosis (RCA) to conventional angiography. Methods This is a retrospective chart review of consecutive patients diagnosed with RCA who underwent 3D SD-OCT between July 2007 and June 2010. Main outcome measures were the diagnostic capabilities of 3D SD-OCT, and the correlation between 3D findings and the features distinguished by conventional angiography. Results Eighteen eyes of 18 patients [five males, 13 females, mean age 79.5±19.4 years (range, 70-93 years)] were included in the analysis. In eyes (n=3) showing a focal staining on angiography, 3D OCT revealed a slight convex prominence of the inner retinal surface in correspondence of a small dome-shaped retinal pigment epithelium (RPE) elevation (which represented the early RCA). In eyes (n=7) showing a "hot spot" without pigment epithelium detachment (PED) on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a well-demarcated prominence of RPE with steep margins (which represented the RCA). In eyes (n=8) showing a "hot spot" with PED on angiography, 3D OCT revealed a convex prominence of the inner retinal surface in correspondence with a convex RPE prominence with a peak at the top. Conclusions 3D SD-OCT provides a map of the retina and RPE, allowing a realistic visualization of the different pathological features in the disease development, and may be able to provide clinically relevant information to complement angiography in the diagnosis of RCA.

Original languageEnglish
Pages (from-to)165-173
Number of pages9
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume250
Issue number2
DOIs
Publication statusPublished - Feb 2012

Keywords

  • Age-related macular degeneration
  • Choroidal neovascularization
  • Fluorescein angiography
  • Indocyanine angiography
  • Retinal angiomatous proliferation
  • Retinal- choroidal anastomosis
  • Scanning laser ophthalmoscopy
  • Three dimensional spectral-domain optical coherence tomography
  • Type 3 neovascularization

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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