Three novel alleles at the HLA-DRB1 locus identified by sequence-based typing

Sara Frison, Elena Longhi, Martina Mantovani, Monica Mantia, Cinzia Tagliaferri, Daniela Di Giorgio, Mario Scalamogna, Francesca Poli

Research output: Contribution to journalArticle

Abstract

We describe here the sequences of 3 new HLA-DRB1 variants officially named DRB1*03:05:03, DRB1*11:10:02, and DRB1*14:86. These novel alleles have been detected in 3 Caucasoid individuals by sequence-based typing. The first and second alleles are the result of a silent mutation, which does not imply any amino acid change. The sequence of DRB1*14:86 exhibits a single nucleotide difference with the allele DRB1*14:01:01 at position 239.

Original languageEnglish
Pages (from-to)67-69
Number of pages3
JournalHuman Immunology
Volume73
Issue number1
DOIs
Publication statusPublished - Jan 2012

Keywords

  • HLA-DRB1*03:05:03
  • HLA-DRB1*11:10:02
  • HLA-DRB1*14:86
  • SBT

ASJC Scopus subject areas

  • Immunology
  • Immunology and Allergy

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