Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy

F. Ansaldi, P. D'Agaro, P. Burgnich, D. De Florentiis, S. Favero, G. Dal Molin, M. Comar, N. Coppola, C. Campello

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The results of the epidemiological and virological surveillance of influenza performed during the 1999/2000, 2000/2001 and 2001/2002 seasons in the northeastern Italy were presented and the relationship between age-specific morbidity rates and circulating strains were discussed.The epidemiological findings pointed out a change in age distribution. During the 1999/2000 season, characterized by a circulation of viruses antigenically close to the vaccine strain, a similar incidence rate in the 0-14 and 15-64-year-old groups was observed, while during the 2001/2002 winter the virus infected mostly children. During 2001/2002 season, B type viruses predominated with at least three distinguishable molecular variants. In particular, B/Victoria/2/87-like viruses re-emerged after more than a decade, and the antibodies elicited by the vaccine strain and by the strains circulating in previous seasons were poor or not protecting. The accumulation of susceptible subjects in young age group during the 1990s, due to the lack of circulation of B/Victoria/2/87-like viruses, was responsible for the unusual morbidity in the 0-14 year group. No circulation of B/Victoria/2/87-like viruses was observed in >64-year-old group during 2001/2002 epidemic, probably due to a long-lasting immunity against viruses belonging to this lineage.

Original languageEnglish
Pages (from-to)885-890
Number of pages6
JournalEuropean Journal of Epidemiology
Volume19
Issue number9
DOIs
Publication statusPublished - Sep 2004

Fingerprint

Human Influenza
Italy
Viruses
Victoria
Vaccines
Morbidity
Cercopithecine Herpesvirus 1
Age Distribution
Immunity
Age Groups
Antibodies
Incidence

Keywords

  • Epidemiology
  • Influenza
  • Virological surveillance

ASJC Scopus subject areas

  • Epidemiology

Cite this

Ansaldi, F., D'Agaro, P., Burgnich, P., De Florentiis, D., Favero, S., Dal Molin, G., ... Campello, C. (2004). Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy. European Journal of Epidemiology, 19(9), 885-890. https://doi.org/10.1023/B:EJEP.0000040529.60673.b7

Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy. / Ansaldi, F.; D'Agaro, P.; Burgnich, P.; De Florentiis, D.; Favero, S.; Dal Molin, G.; Comar, M.; Coppola, N.; Campello, C.

In: European Journal of Epidemiology, Vol. 19, No. 9, 09.2004, p. 885-890.

Research output: Contribution to journalArticle

Ansaldi, F, D'Agaro, P, Burgnich, P, De Florentiis, D, Favero, S, Dal Molin, G, Comar, M, Coppola, N & Campello, C 2004, 'Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy', European Journal of Epidemiology, vol. 19, no. 9, pp. 885-890. https://doi.org/10.1023/B:EJEP.0000040529.60673.b7
Ansaldi, F. ; D'Agaro, P. ; Burgnich, P. ; De Florentiis, D. ; Favero, S. ; Dal Molin, G. ; Comar, M. ; Coppola, N. ; Campello, C. / Three-year (1999-2002) of epidemiological and virological surveillance of influenza in north-east Italy. In: European Journal of Epidemiology. 2004 ; Vol. 19, No. 9. pp. 885-890.
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