Thromboembolic risk in atrial flutter

Giovanni Corrado, A. Sgalambro, A. Mantero, F. Gentile, M. Gasparini, R. Bufalino, A. Morabito, G. Trocino, R. Schiavina, S. Mandorla, R. Mangia, D. Tovena, K. Savino, F. Jacopi, E. M. Pellegrino, F. Agostini, G. Centonze, F. Bovenzi, E. Caprino, G. TadeoM. Santarone

Research output: Contribution to journalArticle

Abstract

Aims: Patients with atrial flutter are believed to be at lower risk of thromboembolism than patients with atrial fibrillation. However, the incidence of atrial thrombi and the need for anticoagulation in patients with atrial flutter is not well established. Methods and Results: A prospective observational multi-centre study was undertaken to assess the frequency of atrial thrombi and spontaneous echocontrast and the prevalence for aortic complex atherosclerotic lesions in a cohort of unselected patients with atrial flutter. We evaluated 134 patients (102 male, aged 70 ± 9 years); exclusion criteria were history of atrial fibrillation, rheumatic mitral valve disease and mitral mechanical prosthesis. The median of atrial flutter duration was 33 days. Twelve patients had been taking warfarin for more than 7 days. One hundred and twenty-four patients (94%) underwent a transoesophageal echocardiogram, which revealed left atrial appendage thrombi in two patients (1.6%) and right atrial thrombi in one patient (1%). At least moderate left atrial echocontrast was found in 16/124 patients (13%). Complex atherosclerotic aortic plaques were detected in 10 patients (8%). Atrial flutter conversion was attempted in 93/134 patients (69%). At the 1-month follow-up, two patients experienced a thromboembolic event following restoration of sinus rhythm. Conclusions: Atrial thrombi and echocontrast, and complex aortic atherosclerotic plaques are relatively uncommon in patients with atrial flutter. Post-cardioversion embolism was observed in two patients in our study population.

Original languageEnglish
Pages (from-to)1042-1051
Number of pages10
JournalEuropean Heart Journal
Volume22
Issue number12
DOIs
Publication statusPublished - 2001

Fingerprint

Atrial Flutter
Thrombosis
Atherosclerotic Plaques
Atrial Fibrillation
Atrial Appendage
Electric Countershock
Thromboembolism
Patient Rights
Warfarin
Embolism
Mitral Valve
Prostheses and Implants

Keywords

  • Atrial flutter
  • Echocardiography
  • Thromboembolism

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Corrado, G., Sgalambro, A., Mantero, A., Gentile, F., Gasparini, M., Bufalino, R., ... Santarone, M. (2001). Thromboembolic risk in atrial flutter. European Heart Journal, 22(12), 1042-1051. https://doi.org/10.1053/euhj.2000.2427

Thromboembolic risk in atrial flutter. / Corrado, Giovanni; Sgalambro, A.; Mantero, A.; Gentile, F.; Gasparini, M.; Bufalino, R.; Morabito, A.; Trocino, G.; Schiavina, R.; Mandorla, S.; Mangia, R.; Tovena, D.; Savino, K.; Jacopi, F.; Pellegrino, E. M.; Agostini, F.; Centonze, G.; Bovenzi, F.; Caprino, E.; Tadeo, G.; Santarone, M.

In: European Heart Journal, Vol. 22, No. 12, 2001, p. 1042-1051.

Research output: Contribution to journalArticle

Corrado, G, Sgalambro, A, Mantero, A, Gentile, F, Gasparini, M, Bufalino, R, Morabito, A, Trocino, G, Schiavina, R, Mandorla, S, Mangia, R, Tovena, D, Savino, K, Jacopi, F, Pellegrino, EM, Agostini, F, Centonze, G, Bovenzi, F, Caprino, E, Tadeo, G & Santarone, M 2001, 'Thromboembolic risk in atrial flutter', European Heart Journal, vol. 22, no. 12, pp. 1042-1051. https://doi.org/10.1053/euhj.2000.2427
Corrado G, Sgalambro A, Mantero A, Gentile F, Gasparini M, Bufalino R et al. Thromboembolic risk in atrial flutter. European Heart Journal. 2001;22(12):1042-1051. https://doi.org/10.1053/euhj.2000.2427
Corrado, Giovanni ; Sgalambro, A. ; Mantero, A. ; Gentile, F. ; Gasparini, M. ; Bufalino, R. ; Morabito, A. ; Trocino, G. ; Schiavina, R. ; Mandorla, S. ; Mangia, R. ; Tovena, D. ; Savino, K. ; Jacopi, F. ; Pellegrino, E. M. ; Agostini, F. ; Centonze, G. ; Bovenzi, F. ; Caprino, E. ; Tadeo, G. ; Santarone, M. / Thromboembolic risk in atrial flutter. In: European Heart Journal. 2001 ; Vol. 22, No. 12. pp. 1042-1051.
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AU - Corrado, Giovanni

AU - Sgalambro, A.

AU - Mantero, A.

AU - Gentile, F.

AU - Gasparini, M.

AU - Bufalino, R.

AU - Morabito, A.

AU - Trocino, G.

AU - Schiavina, R.

AU - Mandorla, S.

AU - Mangia, R.

AU - Tovena, D.

AU - Savino, K.

AU - Jacopi, F.

AU - Pellegrino, E. M.

AU - Agostini, F.

AU - Centonze, G.

AU - Bovenzi, F.

AU - Caprino, E.

AU - Tadeo, G.

AU - Santarone, M.

PY - 2001

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N2 - Aims: Patients with atrial flutter are believed to be at lower risk of thromboembolism than patients with atrial fibrillation. However, the incidence of atrial thrombi and the need for anticoagulation in patients with atrial flutter is not well established. Methods and Results: A prospective observational multi-centre study was undertaken to assess the frequency of atrial thrombi and spontaneous echocontrast and the prevalence for aortic complex atherosclerotic lesions in a cohort of unselected patients with atrial flutter. We evaluated 134 patients (102 male, aged 70 ± 9 years); exclusion criteria were history of atrial fibrillation, rheumatic mitral valve disease and mitral mechanical prosthesis. The median of atrial flutter duration was 33 days. Twelve patients had been taking warfarin for more than 7 days. One hundred and twenty-four patients (94%) underwent a transoesophageal echocardiogram, which revealed left atrial appendage thrombi in two patients (1.6%) and right atrial thrombi in one patient (1%). At least moderate left atrial echocontrast was found in 16/124 patients (13%). Complex atherosclerotic aortic plaques were detected in 10 patients (8%). Atrial flutter conversion was attempted in 93/134 patients (69%). At the 1-month follow-up, two patients experienced a thromboembolic event following restoration of sinus rhythm. Conclusions: Atrial thrombi and echocontrast, and complex aortic atherosclerotic plaques are relatively uncommon in patients with atrial flutter. Post-cardioversion embolism was observed in two patients in our study population.

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KW - Atrial flutter

KW - Echocardiography

KW - Thromboembolism

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