TY - JOUR
T1 - Thrombotic microangiopathy
T2 - What not to learn from a meta-analysis
AU - Noris, Marina
AU - Remuzzi, Giuseppe
PY - 2009/4
Y1 - 2009/4
N2 - A recent meta-analysis concluded that plasma exchange is the most effective intervention for thrombotic thrombocytopenic purpura and that plasma manipulation offers no additional benefit over simple supportive therapy in hemolytic uremic syndrome. These findings must be interpreted with great caution, as response to treatment depends on the underlying disease etiology.
AB - A recent meta-analysis concluded that plasma exchange is the most effective intervention for thrombotic thrombocytopenic purpura and that plasma manipulation offers no additional benefit over simple supportive therapy in hemolytic uremic syndrome. These findings must be interpreted with great caution, as response to treatment depends on the underlying disease etiology.
UR - http://www.scopus.com/inward/record.url?scp=67049161222&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67049161222&partnerID=8YFLogxK
U2 - 10.1038/nrneph.2009.28
DO - 10.1038/nrneph.2009.28
M3 - Article
C2 - 19322181
AN - SCOPUS:67049161222
VL - 5
SP - 186
EP - 188
JO - Nature Reviews Nephrology
JF - Nature Reviews Nephrology
SN - 1759-507X
IS - 4
ER -