Abstract
Highly active antiretroviral therapy (HAART) suppresses viral replication and augments CD4 T cell counts. HAART-associated immune restoration is often difficult to predict. We verified whether increases in CD4 cells, and particularly in cells of the naive phenotype, would be associated in HAART-treated children with thymic volume. Long-term immune reconstitution is significantly better in children with bigger thymuses at the initiation of HAART. Thymic volume has a strong predictive value for the immunological effect of HAART.
Original language | English |
---|---|
Pages (from-to) | 2219-2221 |
Number of pages | 3 |
Journal | AIDS (London, England) |
Volume | 16 |
Issue number | 16 |
DOIs | |
Publication status | Published - Nov 8 2002 |
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology