Thymus plays a fundamental role in the development of immunologic competence. Some 'experiments of nature' indicated that various skin diseases, either infectious or autoimmune, could be correlated to cancer or dysembryogenesis of the thymus. Moreover, the lymphoepithelial structure of the gland and in particular the interactions between immature immune cells and Hassal's corpuscles, which are keratinic structures, suggest that the thymus could represent a 'simulator' of the border between self and the outer environments. In this simulator immature lymphocytes gather for appropriate training.
|Number of pages||5|
|Journal||Annali Italiani di Dermatologia Clinica e Sperimentale|
|Publication status||Published - Jan 1996|
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