Thyroid Follicular Hyperplasia Associated with Massive Extracellular Mucin Deposition

Francesco Nesa, Luca Poggi, Stefano Ferrero, Alessandro Del Gobbo

Research output: Contribution to journalArticlepeer-review


Extensive extracellular mucin deposition is a rare pathological thyroid condition with 6 cases described in literature so far. We report another case of a 67-year-old woman, discussing histopathological features, and review the literature. Our findings showed a diffuse mucin deposition in the stromal compartment of thyroid parenchyma. Histochemical stainings showed positivity for Alcian blue staining, but not for periodic acid-Shiff staining. Our case is peculiar because this mucin deposition was associated with benign nodular hyperplasia, in contrast with the other 6 reports, which described the same stromal alterations associated with benign or malignant thyroid tumors.

Original languageEnglish
Pages (from-to)533-535
Number of pages3
JournalInternational Journal of Surgical Pathology
Issue number6
Publication statusPublished - Sep 1 2017


  • mucin deposition
  • thyroid hyperplasia
  • thyroid stromal alterations

ASJC Scopus subject areas

  • Anatomy
  • Surgery
  • Pathology and Forensic Medicine


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