Thyroid function in gestational trophoblastic tumors.

F. Vergadoro; L. Tabacchi; P. Barbacini; L. Vassena; F. Zanaboni; G. Bolis

Thyroid function in gestational trophoblastic tumors.

F. Vergadoro, L. Tabacchi, P. Barbacini, L. Vassena, F. Zanaboni, G. Bolis

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Abstract

Thyroid function was assessed in a total of 15 cases, 7 of whom had choriocarcinoma and 8 hydatidiform mole, by measuring free T3, free T4, thyroxin-binding globulin (TBG), basal thyroid-stimulating hormone (TSH) and after the thyrotropin-releasing hormone test (delta TSH). Free T3, free T4 and TBG were investigated in the same number of healthy women within the first three months of pregnancy. Only 13.4% of the cases presented elevated levels of free T3 and T4 and TBG; TSH and delta TSH were within normal limits. Both thyroid hormones and TBG returned to within normal limits when beta-human chorionic gonadotropin became undetectable. One patient was found to be hypothyroid. Comparison with the control group showed no significant differences except in TBG levels, which were higher in controls. A significant, direct correlation was found between levels of free T3 and T4 and TBG and the pattern of human chorionic gonadotropin.

Original language	English
Pages (from-to)	205-209
Number of pages	5
Journal	Tumori
Volume	72
Issue number	2
Publication status	Published - Apr 30 1986

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Cancer Research

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Vergadoro, F., Tabacchi, L., Barbacini, P., Vassena, L., Zanaboni, F., & Bolis, G. (1986). Thyroid function in gestational trophoblastic tumors. Tumori, 72(2), 205-209.

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AU - Vergadoro, F.

AU - Tabacchi, L.

AU - Barbacini, P.

AU - Vassena, L.

AU - Zanaboni, F.

AU - Bolis, G.

PY - 1986/4/30

Y1 - 1986/4/30

N2 - Thyroid function was assessed in a total of 15 cases, 7 of whom had choriocarcinoma and 8 hydatidiform mole, by measuring free T3, free T4, thyroxin-binding globulin (TBG), basal thyroid-stimulating hormone (TSH) and after the thyrotropin-releasing hormone test (delta TSH). Free T3, free T4 and TBG were investigated in the same number of healthy women within the first three months of pregnancy. Only 13.4% of the cases presented elevated levels of free T3 and T4 and TBG; TSH and delta TSH were within normal limits. Both thyroid hormones and TBG returned to within normal limits when beta-human chorionic gonadotropin became undetectable. One patient was found to be hypothyroid. Comparison with the control group showed no significant differences except in TBG levels, which were higher in controls. A significant, direct correlation was found between levels of free T3 and T4 and TBG and the pattern of human chorionic gonadotropin.

AB - Thyroid function was assessed in a total of 15 cases, 7 of whom had choriocarcinoma and 8 hydatidiform mole, by measuring free T3, free T4, thyroxin-binding globulin (TBG), basal thyroid-stimulating hormone (TSH) and after the thyrotropin-releasing hormone test (delta TSH). Free T3, free T4 and TBG were investigated in the same number of healthy women within the first three months of pregnancy. Only 13.4% of the cases presented elevated levels of free T3 and T4 and TBG; TSH and delta TSH were within normal limits. Both thyroid hormones and TBG returned to within normal limits when beta-human chorionic gonadotropin became undetectable. One patient was found to be hypothyroid. Comparison with the control group showed no significant differences except in TBG levels, which were higher in controls. A significant, direct correlation was found between levels of free T3 and T4 and TBG and the pattern of human chorionic gonadotropin.

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Thyroid function in gestational trophoblastic tumors.

Abstract

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