Thyroid function in gestational trophoblastic tumors.

F. Vergadoro, L. Tabacchi, P. Barbacini, L. Vassena, F. Zanaboni, G. Bolis

Research output: Contribution to journalArticle

Abstract

Thyroid function was assessed in a total of 15 cases, 7 of whom had choriocarcinoma and 8 hydatidiform mole, by measuring free T3, free T4, thyroxin-binding globulin (TBG), basal thyroid-stimulating hormone (TSH) and after the thyrotropin-releasing hormone test (delta TSH). Free T3, free T4 and TBG were investigated in the same number of healthy women within the first three months of pregnancy. Only 13.4% of the cases presented elevated levels of free T3 and T4 and TBG; TSH and delta TSH were within normal limits. Both thyroid hormones and TBG returned to within normal limits when beta-human chorionic gonadotropin became undetectable. One patient was found to be hypothyroid. Comparison with the control group showed no significant differences except in TBG levels, which were higher in controls. A significant, direct correlation was found between levels of free T3 and T4 and TBG and the pattern of human chorionic gonadotropin.

Original languageEnglish
Pages (from-to)205-209
Number of pages5
JournalTumori
Volume72
Issue number2
Publication statusPublished - Apr 30 1986

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Trophoblastic Neoplasms
Globulins
Thyroxine
Thyroid Gland
Thyrotropin
Chorionic Gonadotropin
Hydatidiform Mole
Choriocarcinoma
Thyrotropin-Releasing Hormone
Thyroid Hormones
Pregnancy
Control Groups

ASJC Scopus subject areas

  • Cancer Research

Cite this

Vergadoro, F., Tabacchi, L., Barbacini, P., Vassena, L., Zanaboni, F., & Bolis, G. (1986). Thyroid function in gestational trophoblastic tumors. Tumori, 72(2), 205-209.

Thyroid function in gestational trophoblastic tumors. / Vergadoro, F.; Tabacchi, L.; Barbacini, P.; Vassena, L.; Zanaboni, F.; Bolis, G.

In: Tumori, Vol. 72, No. 2, 30.04.1986, p. 205-209.

Research output: Contribution to journalArticle

Vergadoro, F, Tabacchi, L, Barbacini, P, Vassena, L, Zanaboni, F & Bolis, G 1986, 'Thyroid function in gestational trophoblastic tumors.', Tumori, vol. 72, no. 2, pp. 205-209.
Vergadoro F, Tabacchi L, Barbacini P, Vassena L, Zanaboni F, Bolis G. Thyroid function in gestational trophoblastic tumors. Tumori. 1986 Apr 30;72(2):205-209.
Vergadoro, F. ; Tabacchi, L. ; Barbacini, P. ; Vassena, L. ; Zanaboni, F. ; Bolis, G. / Thyroid function in gestational trophoblastic tumors. In: Tumori. 1986 ; Vol. 72, No. 2. pp. 205-209.
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