Abstract
Thyroid hormones are necessary to the brain development and their absence results into serious cognitive defects. There is some evidence that thyroid hormones' activity is required in the adult brain for a correct neuronal net orchestration as well. The bonds between mood disorders and thyroid imbalances are reviewed in this paper, the molecular background of these poorly defined boundaries is exposed, along with the putative mechanisms that underlie the antidepressant effect of thyroid hormones in the event of augmentation strategy.
| Original language | English |
|---|---|
| Pages (from-to) | 103-111 |
| Number of pages | 9 |
| Journal | Clinical Neuropsychiatry |
| Volume | 6 |
| Issue number | 3 |
| Publication status | Published - 2009 |
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Keywords
- Cognitive defects
- Mood disorders
- Thyroid hormones
ASJC Scopus subject areas
- Psychiatry and Mental health
Cite this
Liappas, I., Drago, A., Zisakis, A. K., Malitas, P. N., Zisaki, A. K., Kalofoutis, A., Lea, R. W., Pantos, K., & Serretti, A. (2009). Thyroid hormone and affective disorders. Clinical Neuropsychiatry, 6(3), 103-111.