Abstract
Catheter-related bacteremias carry high mortality rates in hematological patients. When a multidrug-resistant microorganism is involved, the catheter should ideally be removed; however, this approach is not always possible. Tigecycline lock therapy was used in two pediatric oncohematological patients with intravascular catheter-related infection due to KPC-producing Klebsiella pneumoniae. The catheter was salvaged in both cases, and the patients were later discharged. Our experience suggests the usefulness of this approach in treating this type of infection.
| Original language | English |
|---|---|
| Pages (from-to) | 7919-7920 |
| Number of pages | 2 |
| Journal | Antimicrobial Agents and Chemotherapy |
| Volume | 59 |
| Issue number | 12 |
| DOIs | |
| Publication status | Published - Dec 1 2015 |
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ASJC Scopus subject areas
- Pharmacology (medical)
- Pharmacology
- Infectious Diseases
Cite this
Tigecycline lock therapy for catheter-related bloodstream infection caused by KPC-producing Klebsiella pneumoniae in two pediatric hematological patients. / Foresti, Sergio; Di Bella, Stefano; Rovelli, Attilio; Sala, Alessandra; Verna, Marta; Bisi, Luca; Nisii, Carla; Gori, Andrea.
In: Antimicrobial Agents and Chemotherapy, Vol. 59, No. 12, 01.12.2015, p. 7919-7920.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Tigecycline lock therapy for catheter-related bloodstream infection caused by KPC-producing Klebsiella pneumoniae in two pediatric hematological patients
AU - Foresti, Sergio
AU - Di Bella, Stefano
AU - Rovelli, Attilio
AU - Sala, Alessandra
AU - Verna, Marta
AU - Bisi, Luca
AU - Nisii, Carla
AU - Gori, Andrea
PY - 2015/12/1
Y1 - 2015/12/1
N2 - Catheter-related bacteremias carry high mortality rates in hematological patients. When a multidrug-resistant microorganism is involved, the catheter should ideally be removed; however, this approach is not always possible. Tigecycline lock therapy was used in two pediatric oncohematological patients with intravascular catheter-related infection due to KPC-producing Klebsiella pneumoniae. The catheter was salvaged in both cases, and the patients were later discharged. Our experience suggests the usefulness of this approach in treating this type of infection.
AB - Catheter-related bacteremias carry high mortality rates in hematological patients. When a multidrug-resistant microorganism is involved, the catheter should ideally be removed; however, this approach is not always possible. Tigecycline lock therapy was used in two pediatric oncohematological patients with intravascular catheter-related infection due to KPC-producing Klebsiella pneumoniae. The catheter was salvaged in both cases, and the patients were later discharged. Our experience suggests the usefulness of this approach in treating this type of infection.
UR - http://www.scopus.com/inward/record.url?scp=84954475274&partnerID=8YFLogxK
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U2 - 10.1128/AAC.01855-15
DO - 10.1128/AAC.01855-15
M3 - Article
VL - 59
SP - 7919
EP - 7920
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
SN - 0066-4804
IS - 12
ER -