Time course of 3H-reserpine levels in brains of normal and tetrabenazine-pretreated rats

L. Manara, S. Garattini

Research output: Contribution to journalArticle

Abstract

Measurements of reserpine in the brain of normal and tetrabenazine-pretreated rats supply direct evidence in favor of the view that these drugs compete at the level of a common target. In addition the results of the present drug interaction study underline the relevance of the long-lasting concentrations of reserpine in the brain for explaining the functional modifications induced by its administration.

Original languageEnglish
Pages (from-to)139-141
Number of pages3
JournalEuropean Journal of Pharmacology
Volume2
Issue number2
Publication statusPublished - Nov 1967

Keywords

  • Tritium labeled reserpine: brain concentration in the rat Tetrabenazine Tissue catecholamines

ASJC Scopus subject areas

  • Pharmacology
  • Cellular and Molecular Neuroscience

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