Measurements of reserpine in the brain of normal and tetrabenazine-pretreated rats supply direct evidence in favor of the view that these drugs compete at the level of a common target. In addition the results of the present drug interaction study underline the relevance of the long-lasting concentrations of reserpine in the brain for explaining the functional modifications induced by its administration.
|Number of pages||3|
|Journal||European Journal of Pharmacology|
|Publication status||Published - Nov 1967|
- Tritium labeled reserpine: brain concentration in the rat Tetrabenazine Tissue catecholamines
ASJC Scopus subject areas
- Cellular and Molecular Neuroscience