Time course of pressure and flow in ascending aorta during ejection

Stefano Perlini; Pier Luigi Soldà; Massimo Piepoli; Alessandro Calciati; Maurizio Paro; Germano Marchetti; Frank Meno; Giorgio Finardi; Luciano Bernardi

doi:10.1016/0167-5273(91)90092-4

Time course of pressure and flow in ascending aorta during ejection

Stefano Perlini, Pier Luigi Soldà, Massimo Piepoli, Alessandro Calciati, Maurizio Paro, Germano Marchetti, Frank Meno, Giorgio Finardi, Luciano Bernardi

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

To analyze aortic flow and pressure relationships, 10 closed-chest anaesthetised dogs were instrumented with electromagnetic aortic flow probes and micromanometers in the left ventricle and ascending aorta. Left ventricular ejection time was divided into: time to peak flow (T1) (both pressure and flow rising), peak flow to peak pressure time (T2) (pressure rising, flow decreasing), and peak pressure to dicrotic notch time (T3) (pressure and flow both decreasing). These time intervals were expressed as percent of total ejection time. Load-active interventions rose markedly T2 (from 4.2 ± 5.5 to 19.4 ± 3.5 after phenylephrine (p1-adrenergic stimulation significantly shortens T2. Dynamic pressure-flow relationship is thus continuously changing during ejection. T2 seems to be inversely related to the efficiency of left ventricular ejection dynamics.

Original language	English
Pages (from-to)	169-179
Number of pages	11
Journal	International Journal of Cardiology
Volume	30
Issue number	2
DOIs	https://doi.org/10.1016/0167-5273(91)90092-4
Publication status	Published - 1991

Keywords

Afterload
Aortic pressure-flow relationships
Ejection dynamics
Preload

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Access to Document

10.1016/0167-5273(91)90092-4

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Time course of pressure and flow in ascending aorta during ejection. / Perlini, Stefano; Soldà, Pier Luigi; Piepoli, Massimo; Calciati, Alessandro; Paro, Maurizio; Marchetti, Germano; Meno, Frank; Finardi, Giorgio; Bernardi, Luciano.

In: International Journal of Cardiology, Vol. 30, No. 2, 1991, p. 169-179.

Research output: Contribution to journal › Article › peer-review

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AU - Soldà, Pier Luigi

AU - Piepoli, Massimo

AU - Calciati, Alessandro

AU - Paro, Maurizio

AU - Marchetti, Germano

AU - Meno, Frank

AU - Finardi, Giorgio

AU - Bernardi, Luciano

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