Time-dependent increase of glomerular filtration rate after oral protein load

Evidence for diurnal variations in renal response

C. Buzio, P. Quaretti, L. Arisi, A. Negro, R. Barani, M. G. Alquati

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Seven healthy male volunteers were studied to test the effect of timing of an oral protein load on renal function. Creatinine clearance (Ccr) was measured during the 4-h period after administration of 72 g of protein in the form of cooked red meat at 1200 hours (lunch protein load, PL) and at 2000 hours (supper PL) the next evening. A low-protein meal in the form of vegetables was given as a control load at 2000 hours on the first day (supper control load, CL) and at 1200 hours on the second day (lunch CL). The 12-h night-time Ccr at fasting was used as the baseline reference value. After the lunch PL, Ccr (mean 127±6.8 ml/min) was 45% (p

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalScandinavian Journal of Clinical and Laboratory Investigation
Volume48
Issue number1
DOIs
Publication statusPublished - 1988

Fingerprint

Glomerular Filtration Rate
Kidney
Lunch
Meals
Creatinine
Proteins
Meats
Vegetables
Fasting
Healthy Volunteers
Reference Values

Keywords

  • Circadian rhythm
  • Creatinine clearance
  • Glomerular hyperfiltration
  • Protein intake
  • Renal functional reserve

ASJC Scopus subject areas

  • Clinical Biochemistry

Cite this

Time-dependent increase of glomerular filtration rate after oral protein load : Evidence for diurnal variations in renal response. / Buzio, C.; Quaretti, P.; Arisi, L.; Negro, A.; Barani, R.; Alquati, M. G.

In: Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 48, No. 1, 1988, p. 15-19.

Research output: Contribution to journalArticle

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