Time-dependent increase of glomerular filtration rate after oral protein load: Evidence for diurnal variations in renal response

C. Buzio; P. Quaretti; L. Arisi; A. Negro; R. Barani; M. G. Alquati

doi:10.3109/00365518809085388

Time-dependent increase of glomerular filtration rate after oral protein load: Evidence for diurnal variations in renal response

C. Buzio, P. Quaretti, L. Arisi, A. Negro, R. Barani, M. G. Alquati

IRCCS Fondazione Policlinico San Matteo

Research output: Contribution to journal › Article › peer-review

Abstract

Seven healthy male volunteers were studied to test the effect of timing of an oral protein load on renal function. Creatinine clearance (Ccr) was measured during the 4-h period after administration of 72 g of protein in the form of cooked red meat at 1200 hours (lunch protein load, PL) and at 2000 hours (supper PL) the next evening. A low-protein meal in the form of vegetables was given as a control load at 2000 hours on the first day (supper control load, CL) and at 1200 hours on the second day (lunch CL). The 12-h night-time Ccr at fasting was used as the baseline reference value. After the lunch PL, Ccr (mean 127±6.8 ml/min) was 45% (p

Original language	English
Pages (from-to)	15-19
Number of pages	5
Journal	Scandinavian Journal of Clinical and Laboratory Investigation
Volume	48
Issue number	1
DOIs	https://doi.org/10.3109/00365518809085388
Publication status	Published - 1988

Keywords

Circadian rhythm
Creatinine clearance
Glomerular hyperfiltration
Protein intake
Renal functional reserve

ASJC Scopus subject areas

Clinical Biochemistry

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10.3109/00365518809085388

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Time-dependent increase of glomerular filtration rate after oral protein load : Evidence for diurnal variations in renal response. / Buzio, C.; Quaretti, P.; Arisi, L.; Negro, A.; Barani, R.; Alquati, M. G.

In: Scandinavian Journal of Clinical and Laboratory Investigation, Vol. 48, No. 1, 1988, p. 15-19.

Research output: Contribution to journal › Article › peer-review

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