Time restricted feeding and mental health: a review of possible mechanisms on affective and cognitive disorders

Walter Currenti, Justyna Godos, Sabrina Castellano, Maria P. Mogavero, Raffaele Ferri, Filippo Caraci, Giuseppe Grosso, Fabio Galvano

Research output: Contribution to journalArticlepeer-review

Abstract

In the last decades, a high increase in life expectancy not adequately balanced by an improvement in the quality of life has been observed, leading possibly to an increase in the prevalence of affective and cognitive disorders related to aging, such as depression, cognitive impairment, dementia and Alzheimer’s disease. As mental illnesses have multifactorial aetiologies, many modifiable factors including lifestyle and nutrition play an essential role. Among nutritional factors, intermittent fasting has emerged as an innovative strategy to prevent and treat mental health disorders, sleep disturbances and cognitive impairment. Among all types of intermittent fasting regimens, the time restricted feeding appears to be the most promising protocol as it allows to induce benefits of a total fasting without reducing global calories and nutrients intake. This review summarises the evidence on the effect of time restricted feeding towards brain health, emphasising its role on brain signalling, neurogenesis and synaptic plasticity.

Original languageEnglish
JournalInternational Journal of Food Sciences and Nutrition
DOIs
Publication statusAccepted/In press - 2020

Keywords

  • brain
  • circadian rhythm
  • cognitive
  • mental health
  • sleep
  • Time restricted feeding

ASJC Scopus subject areas

  • Food Science

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