Time-warping averaging for quantitative evaluation of changes in LV function

E. G. Caiani, M. Turiel, A. Porta, S. Muzzupappa, B. Gottardi, G. Baselli, S. Cerutti

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Signal averaged acoustic quantification (SAAQ) with time-warping (TW) preserves the morphology of SAAQ waveforms allowing reliable noninvasive quantification of amplitude- and timing-indexes of left ventricular (LV) function, which cannot be assessed with simple signal averaging. We tested the ability of this technique to track pharmacologically induced changes in LV function during residual viability study. LV volume signals obtained (Sonos 5500) in 10 patients with dilated cardiomyopathy under control conditions and during low-dose dobutamine infusion (10 mcg/kg/min) were digitized at 300 Hz. In each subject and for each experimental condition LV volume signals were averaged (16 consecutive beats) with the TW technique. Averaged waveforms and time-derivatives were used to identify the phases of LV filling and calculated end-systolic and end-diastolic volumes, stroke, peak rapid and peak atrial filling rates, peak ejection rate, duration of heart cycle, systole, rapid filling and atrial filling phases. The calculated indices reflected the low-dose dobutamine-induced changes in LV function, evidencing variations both in rapid filling and systolic phases. Signal averaging with TW allows reliable calculation of indices of LV systolic and diastolic function, and can be used to monitor their changes related to residual viability examinations.

Original languageEnglish
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Pages84-85
Number of pages2
Volume1
Publication statusPublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Other

OtherProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS)
CountryUnited States
CityHouston, TX
Period10/23/0210/26/02

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Keywords

  • Acoustic quantification
  • Echocardiography
  • LV function
  • Signal averaging
  • Time-warping

ASJC Scopus subject areas

  • Bioengineering

Cite this

Caiani, E. G., Turiel, M., Porta, A., Muzzupappa, S., Gottardi, B., Baselli, G., & Cerutti, S. (2002). Time-warping averaging for quantitative evaluation of changes in LV function. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 1, pp. 84-85)