Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: A dose-finding study

C. Ficorella; M. F. Morelli; E. Ricevuto; K. Cannita; G. Porzio; P. Lanfiuti Baldi; G. Cianci; Z. C. Di Rocco; C. Natoli; N. Tinari; F. De Galitiis; F. Calista; P. Marchetti

Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: A dose-finding study

C. Ficorella, M. F. Morelli, E. Ricevuto, K. Cannita, G. Porzio, P. Lanfiuti Baldi, G. Cianci, Z. C. Di Rocco, C. Natoli, N. Tinari, F. De Galitiis, F. Calista, P. Marchetti

Istituto Dermopatico dell'Immacolata , IDI

Research output: Contribution to journal › Article › peer-review

Abstract

A dose-finding study was undertaken to determine the maximum-tolerated dose, and the recommended dose of docetaxel in combination with 12-h timed (22:00-10:00) flat infusion of 5-fluorouracil (5-FU) in metastatic breast cancer patients. This schedule seems to reduce the occurrence of stomatitis of the docetaxel and infusional 5-FU regimen.

Original language	English
Pages (from-to)	618-620
Number of pages	3
Journal	British Journal of Cancer
Volume	91
Issue number	4
Publication status	Published - Aug 16 2004

Keywords

5-fluorouracil
Breast cancer
Docetaxel

ASJC Scopus subject areas

Cancer Research
Oncology

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Ficorella, C., Morelli, M. F., Ricevuto, E., Cannita, K., Porzio, G., Lanfiuti Baldi, P., Cianci, G., Di Rocco, Z. C., Natoli, C., Tinari, N., De Galitiis, F., Calista, F., & Marchetti, P. (2004). Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: A dose-finding study. British Journal of Cancer, 91(4), 618-620.

Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer : A dose-finding study. / Ficorella, C.; Morelli, M. F.; Ricevuto, E.; Cannita, K.; Porzio, G.; Lanfiuti Baldi, P.; Cianci, G.; Di Rocco, Z. C.; Natoli, C.; Tinari, N.; De Galitiis, F.; Calista, F.; Marchetti, P.

In: British Journal of Cancer, Vol. 91, No. 4, 16.08.2004, p. 618-620.

Research output: Contribution to journal › Article › peer-review

Ficorella, C, Morelli, MF, Ricevuto, E, Cannita, K, Porzio, G, Lanfiuti Baldi, P, Cianci, G, Di Rocco, ZC, Natoli, C, Tinari, N, De Galitiis, F, Calista, F & Marchetti, P 2004, 'Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer: A dose-finding study', British Journal of Cancer, vol. 91, no. 4, pp. 618-620.

Ficorella, C. ; Morelli, M. F. ; Ricevuto, E. ; Cannita, K. ; Porzio, G. ; Lanfiuti Baldi, P. ; Cianci, G. ; Di Rocco, Z. C. ; Natoli, C. ; Tinari, N. ; De Galitiis, F. ; Calista, F. ; Marchetti, P. / Timed flat infusion of 5-fluorouracil increases the tolerability of 5-fluorouracil/docetaxel regimen in metastatic breast cancer : A dose-finding study. In: British Journal of Cancer. 2004 ; Vol. 91, No. 4. pp. 618-620.

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