Time–frequency analyses of reaction times and theta/beta EEG ratio in pediatric patients with traumatic brain injury: A preliminary study

Simone Gazzellini, Antonio Napolitano, Graziella Bauleo, Eleonora Bisozzi, Maria Luisa Lispi, Eleonora Ardu, Enrico Castelli, Francesco Benso

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: The literature on patients with attention deficit reports peculiar reaction time (RT) oscillation at very low frequencies (VLFO=0.06–0.2 Hz). The data were explained as default mode network (DMN) intrusion in goal-oriented activity. The present study investigates whether a pattern of recurrent lapses in attention can be detected in TBI patients and whether VLFO can be generalized to the sustained attention deficit, regardless of etiology. Methods: Groups of pediatric TBIs and healthy controls performed four attentional tasks. RT and theta/beta timeseries were subjected to wavelet analyses. Results: Significant high-power VLFOs were recorded in patient group performances but not in those of controls, both for RTs and theta/beta in all the tasks. Conclusion: This preliminary study suggests that central-midline theta/beta ratio could be considered a neurophysiological correlate of RT variability and that the general continuous goal-oriented activity can be cross-etiologically affected by recurrent lapses in attention regardless of the specific cognitive component involved.

Original languageEnglish
Pages (from-to)1-15
Number of pages15
JournalDevelopmental Neurorehabilitation
DOIs
Publication statusAccepted/In press - Sep 15 2016

Keywords

  • Attention
  • children
  • EEG spectral analysis
  • RT variability
  • TBI

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Rehabilitation
  • Developmental Neuroscience

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