TY - JOUR
T1 - Timing and Strategy for Weaning from Venoarterial ECMO are Complex Issues
AU - Pappalardo, Federico
AU - Pieri, Marina
AU - Arnaez Corada, Blanca
AU - Ajello, Silvia
AU - Melisurgo, Giulio
AU - De Bonis, Michele
AU - Zangrillo, Alberto
PY - 2015
Y1 - 2015
N2 - Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or end-organ recovery. The aim of the study was to address the weaning procedure, analyzing the hemodynamic and echocardiographic picture of patients weaned and to identify predictors of poor outcome among this population. Design Observational study. Setting University hospital. Participants One hundred twenty-nine VA ECMO cases. Interventions None. Measurements and Main Results Forty-nine patients (38%) were weaned, 7 (5.4%) were bridged to a ventricular assist device, and 6 (5.2%) were listed for heart transplantation. Weaned patients showed a significant increase of pulse pressure (35 [0-50] mmHg before ECMO, 59 [53-67] mmHg at weaning, 61 [51-76] mmHg after ECMO (p
AB - Objective Weaning from venoarterial extracorporeal membrane oxygenation (VA ECMO) usually is performed without clear guidelines; yet, patients still die after removal of extracorporeal circulation because of inadequate heart or end-organ recovery. The aim of the study was to address the weaning procedure, analyzing the hemodynamic and echocardiographic picture of patients weaned and to identify predictors of poor outcome among this population. Design Observational study. Setting University hospital. Participants One hundred twenty-nine VA ECMO cases. Interventions None. Measurements and Main Results Forty-nine patients (38%) were weaned, 7 (5.4%) were bridged to a ventricular assist device, and 6 (5.2%) were listed for heart transplantation. Weaned patients showed a significant increase of pulse pressure (35 [0-50] mmHg before ECMO, 59 [53-67] mmHg at weaning, 61 [51-76] mmHg after ECMO (p
KW - echocardiography
KW - hemodynamics
KW - venoarterial ECMO
KW - weaning
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U2 - 10.1053/j.jvca.2014.12.011
DO - 10.1053/j.jvca.2014.12.011
M3 - Article
C2 - 25836952
AN - SCOPUS:84942838406
VL - 29
SP - 906
EP - 911
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
SN - 1053-0770
IS - 4
ER -