TY - JOUR
T1 - Timing of right parietal and frontal cortex activity in visuo-spatial perception
T2 - A TMS study in normal individuals
AU - Fierro, Brigida
AU - Brighina, Filippo
AU - Piazza, Aurelio
AU - Oliveri, Massimiliano
AU - Bisiach, Edoardo
PY - 2001/8/8
Y1 - 2001/8/8
N2 - In a recent study we showed that repetitive transcranial magnetic stimulation (rTMS) with train duration of 400 ms over right frontal and right posterior parietal cortices gives rise to transitory contralateral visuo-spatial neglect in normal subjects. In the present experiment we investigated whether using single-pulse TMS it is possible to obtain information about the timing of cortical activity related to spatial cognition. Nine healthy subjects performed in baseline condition and during TMS a tachistoscopic task, requiring a forced-choice estimation of the length of the two segments of prebisected horizontal lines. Single-pulse TMS was triggered at various time intervals (150 ms, 225 ms, 300 ms) after visual stimulus onset with a focal coil over P6 and F4 (according to 10/20 EEG system). Relative transitory rightward bias was observed only when parietal TMS was delivered 150 ms after visual stimulus presentation. Frontal stimulation induced no effect on visuo-spatial perception with the time intervals explored.
AB - In a recent study we showed that repetitive transcranial magnetic stimulation (rTMS) with train duration of 400 ms over right frontal and right posterior parietal cortices gives rise to transitory contralateral visuo-spatial neglect in normal subjects. In the present experiment we investigated whether using single-pulse TMS it is possible to obtain information about the timing of cortical activity related to spatial cognition. Nine healthy subjects performed in baseline condition and during TMS a tachistoscopic task, requiring a forced-choice estimation of the length of the two segments of prebisected horizontal lines. Single-pulse TMS was triggered at various time intervals (150 ms, 225 ms, 300 ms) after visual stimulus onset with a focal coil over P6 and F4 (according to 10/20 EEG system). Relative transitory rightward bias was observed only when parietal TMS was delivered 150 ms after visual stimulus presentation. Frontal stimulation induced no effect on visuo-spatial perception with the time intervals explored.
KW - Neglect
KW - Right frontal cortex
KW - Right parietal cortex
KW - TMS
KW - Visuo-spatial perception timing
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M3 - Article
C2 - 11496157
AN - SCOPUS:0035828119
VL - 12
SP - 2605
EP - 2607
JO - NeuroReport
JF - NeuroReport
SN - 0959-4965
IS - 11
ER -