Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer

G Mangili, E Papaleo, C Sigismondi, R Masciangelo, V Sarais, Veronica Giorgione, R Nale, L Privitera, L Carnelli, V Di Mattei, M Candiani

Research output: Contribution to journalArticlepeer-review


Purpose: Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods: A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results: Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (p
Original languageEnglish
Pages (from-to)182-186
Number of pages5
Issue number2
Publication statusPublished - 2017


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