Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer

G Mangili; E Papaleo; C Sigismondi; R Masciangelo; V Sarais; Veronica Giorgione; R Nale; L Privitera; L Carnelli; V Di Mattei; M Candiani

doi:10.5301/tj.5000586

Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer

G Mangili, E Papaleo, C Sigismondi, R Masciangelo, V Sarais, Veronica Giorgione, R Nale, L Privitera, L Carnelli, V Di Mattei, M Candiani

IRCCS Ospedale San Raffaele

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods: A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results: Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (p

Original language	English
Pages (from-to)	182-186
Number of pages	5
Journal	Tumori
Volume	103
Issue number	2
DOIs	https://doi.org/10.5301/tj.5000586
Publication status	Published - 2017

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title = "Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer",

abstract = "Purpose: Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods: A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results: Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (p",

author = "G Mangili and E Papaleo and C Sigismondi and R Masciangelo and V Sarais and Veronica Giorgione and R Nale and L Privitera and L Carnelli and {Di Mattei}, V and M Candiani",

year = "2017",

doi = "10.5301/tj.5000586",

language = "English",

volume = "103",

pages = "182--186",

journal = "Tumori",

issn = "0300-8916",

publisher = "SAGE Publications Ltd",

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TY - JOUR

T1 - Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer

AU - Mangili, G

AU - Papaleo, E

AU - Sigismondi, C

AU - Masciangelo, R

AU - Sarais, V

AU - Giorgione, Veronica

AU - Nale, R

AU - Privitera, L

AU - Carnelli, L

AU - Di Mattei, V

AU - Candiani, M

PY - 2017

Y1 - 2017

N2 - Purpose: Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods: A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results: Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (p

AB - Purpose: Anticancer treatment-related infertility is preventable with oocyte cryopreservation, but this is often not considered a relevant issue, due to lack of knowledge and time. The aim of this study is to prove that adequate organization of an Oncofertility Unit and the use of new protocols for controlled ovarian stimulation (COS) can reduce the time required by the procedure, encouraging consultants and patients to preserve fertility before gonadotoxic treatments. Methods: A total of 125 patients diagnosed with malignant tumors were referred to the Oncofertility Unit of San Raffaele Hospital: 52 patients between April 2011 and October 2013 and 73 patients between October 2013 and November 2015. The 2 periods differ in office organization and type of COS protocol used. Results: Between the 2 periods, a reduction in the mean number of days required from first counseling to the initiation (6.45 ± 1.058 vs 1.61 ± 0.228) and the end of the COS (17.83 ± 1.227 vs 13.70 ± 0.393) was observed (p

U2 - 10.5301/tj.5000586

DO - 10.5301/tj.5000586

M3 - Article

VL - 103

SP - 182

EP - 186

JO - Tumori

JF - Tumori

SN - 0300-8916

IS - 2

ER -

Timing should no longer be an obstacle to oocyte cryopreservation in patients with cancer

Abstract

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