Tirofiban as treatment for acute retinal artery occlusion following internal carotid artery flow diverter implantation

Luisa Pierro, Carlo La Spina, Federico Corvi, Maria V. Cicinelli, Francesco Scomazzoni, Alberto Cappelletti, Francesco Bandello

Research output: Contribution to journalArticle


Purpose: To report a favorable outcome of branch retinal artery occlusion (BRAO) treated by means of early administration of tirofiban, a glycoprotein IIb-IIIa platelet receptor inhibitor. Methods: Case report. Results: A 65-year-old woman developed dramatic visual impairment in her left eye secondary to BRAO after left internal carotid artery endovascular reconstruction with flow diverter stent implant; visual acuity was hand motion. A dose of intravenous tirofiban was injected 10 minutes after symptoms onset. Fourteen hours after drug infusion, retinal fluorescein angiography revealed a well-perfused macula with a partial reperfusion of the inferior temporal branch of the central retinal artery; visual acuity was 20/20 in both eyes. Conclusions: This case supports the effectiveness of tirofiban in secondary BRAO in neurosurgery and may open its usage to further research.

Original languageEnglish
Pages (from-to)e74-e76
JournalEuropean Journal of Ophthalmology
Issue number4
Publication statusPublished - Jul 1 2016



  • Carotid aneurysm
  • Glycoprotein iib-iiia inhibitors
  • Retinal artery occlusion
  • Tirofiban

ASJC Scopus subject areas

  • Ophthalmology

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