Tissue Doppler imaging of the fetal heart

D. Paladini, A. Lamberti, A. Teodoro, M. Arienzo, A. Tartaglione, P. Martinelli

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Objectives: The objectives of this study were: (i) to assess the feasibility of a tissue Doppler imaging (TDI) evaluation in the fetus, (ii) to identify color-TDI patterns consistent with the various phases of the cardiac cycle; and (iii) to assess myocardial velocities and the myocardial velocity gradient. Methods: Eighty-nine normal fetuses between the 17th and the 37th week of gestation were studied. Color-TDI was superimposed on an apical four-chamber view of the fetal heart and three cardiac cycles captured in cine-loop format. By reviewing the cine-loop strip, color patterns consistent with the various phases of the cardiac cycle were identified. The procedure was then repeated with a transverse four-chamber view. On each frame corresponding to mid-systole, early and late diastole, myocardial velocities were calculated at the subepicardial and sub-endocardial layer and regressed against gestational age. Statistics included correlation and regression analysis, calculation of the 95% confidence intervals and of the Cronbach's alpha reliability coefficient for repeated observations. Results: TDI examination is acceptably reproducible in the fetus. We were able to identify color-TDI patterns depicting the systolic contraction wave, ventricular relaxation and atrial contraction. Statistical evaluation demonstrated that: all variables (systolic right and left subendocardial and subepicardial velocities, early diastolic right and left subendocardial and subepicardial velocities, end diastolic right and left subendocardial velocities, right subepicardial velocities) except end-diastolic right and left subepicardial velocities, showed a positive correlation with advancing gestational age, subendocardial velocities were higher than subepicardial ones throughout the cardiac cycle in both ventricles; systolic myocardial velocities were higher in the left ventricle whereas early diastolic velocities were higher in the right ventricle; and the ratio between early and late diastolic subendocardial velocities (EM/AM) was constantly <1 and did not change with advancing gestational age. Conclusions: TDI evaluation of the fetal heart is feasible and reproducible. Color-TDI is able to identify the various phases of the cardiac cycle. Quantitative evaluation of myocardial velocities has shown also in the fetus the existence of the myocardial velocity gradient found in postnatal life.

Original languageEnglish
Pages (from-to)530-535
Number of pages6
JournalUltrasound in Obstetrics and Gynecology
Volume16
Issue number6
DOIs
Publication statusPublished - 2000

Fingerprint

Fetal Heart
Color
Fetus
Gestational Age
fetuses
Heart Ventricles
color
cycles
Diastole
evaluation
Systole
contraction
chambers
diastole
systole
Regression Analysis
Confidence Intervals
Pregnancy
gradients
reviewing

Keywords

  • Diastolic function
  • Fetus
  • Myocardium
  • Tissue Doppler imaging

ASJC Scopus subject areas

  • Obstetrics and Gynaecology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology
  • Reproductive Medicine
  • Acoustics and Ultrasonics

Cite this

Paladini, D., Lamberti, A., Teodoro, A., Arienzo, M., Tartaglione, A., & Martinelli, P. (2000). Tissue Doppler imaging of the fetal heart. Ultrasound in Obstetrics and Gynecology, 16(6), 530-535. https://doi.org/10.1046/j.1469-0705.2000.00251.x

Tissue Doppler imaging of the fetal heart. / Paladini, D.; Lamberti, A.; Teodoro, A.; Arienzo, M.; Tartaglione, A.; Martinelli, P.

In: Ultrasound in Obstetrics and Gynecology, Vol. 16, No. 6, 2000, p. 530-535.

Research output: Contribution to journalArticle

Paladini, D, Lamberti, A, Teodoro, A, Arienzo, M, Tartaglione, A & Martinelli, P 2000, 'Tissue Doppler imaging of the fetal heart', Ultrasound in Obstetrics and Gynecology, vol. 16, no. 6, pp. 530-535. https://doi.org/10.1046/j.1469-0705.2000.00251.x
Paladini, D. ; Lamberti, A. ; Teodoro, A. ; Arienzo, M. ; Tartaglione, A. ; Martinelli, P. / Tissue Doppler imaging of the fetal heart. In: Ultrasound in Obstetrics and Gynecology. 2000 ; Vol. 16, No. 6. pp. 530-535.
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AU - Martinelli, P.

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