Abstract
Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff
| Original language | Italian |
|---|---|
| Pages (from-to) | 364-371 |
| Number of pages | 8 |
| Journal | Reumatismo |
| Volume | 54 |
| Issue number | 4 |
| Publication status | Published - 2002 |
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ASJC Scopus subject areas
- Rheumatology
Cite this
Applicazioni dell'ingegneria tissutale : Riparazione di lesioni cartilaginee con condrociti autologhi. / Grigolo, B.; Roseti, L.; Fiorini, M.; De Franceschi, L.; Facchini, Andrea.
In: Reumatismo, Vol. 54, No. 4, 2002, p. 364-371.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Applicazioni dell'ingegneria tissutale
T2 - Riparazione di lesioni cartilaginee con condrociti autologhi
AU - Grigolo, B.
AU - Roseti, L.
AU - Fiorini, M.
AU - De Franceschi, L.
AU - Facchini, Andrea
PY - 2002
Y1 - 2002
N2 - Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff
AB - Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff
KW - Autologous chondrocytes
KW - Biomaterial
KW - Transplantation
UR - http://www.scopus.com/inward/record.url?scp=0036904637&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036904637&partnerID=8YFLogxK
M3 - Articolo
C2 - 12563373
AN - SCOPUS:0036904637
VL - 54
SP - 364
EP - 371
JO - Reumatismo
JF - Reumatismo
SN - 0048-7449
IS - 4
ER -