Applicazioni dell'ingegneria tissutale: Riparazione di lesioni cartilaginee con condrociti autologhi

Translated title of the contribution: Tissue engineering applications: Cartilage lesions repair by the use of autologous chondrocytes

B. Grigolo, L. Roseti, M. Fiorini, L. De Franceschi, Andrea Facchini

Research output: Contribution to journalArticle

Abstract

Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff

Original languageItalian
Pages (from-to)364-371
Number of pages8
JournalReumatismo
Volume54
Issue number4
Publication statusPublished - 2002

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ASJC Scopus subject areas

  • Rheumatology

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