Abstract
Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff
| Original language | Italian |
|---|---|
| Pages (from-to) | 364-371 |
| Number of pages | 8 |
| Journal | Reumatismo |
| Volume | 54 |
| Issue number | 4 |
| Publication status | Published - 2002 |
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ASJC Scopus subject areas
- Rheumatology
Cite this
Grigolo, B., Roseti, L., Fiorini, M., De Franceschi, L., & Facchini, A. (2002). Applicazioni dell'ingegneria tissutale: Riparazione di lesioni cartilaginee con condrociti autologhi. Reumatismo, 54(4), 364-371.