Abstract
Promising new therapies based on tissue engineering have been recently developed for cartilage repair. The association of biomaterials with autologous chondrocytes expanded in vitro can represent a useful tool to regenerate this tissue. The scaffolds utilised in such therapeutical applications should provide a pre-formed three-dimensional shape, prevent cells from floating out of the defect, have sufficient mechanical strength, facilitate uniform spread of cells and stimulate the phenotype of transplanted cells. Hyaff°-11 is a hyaluronic-acid based biodegradable polymer, that has been shown to provide successful cell carrier for tissue-engineered repair. From our findings we can state that human chondrocytes seeded on Hyaff
| Translated title of the contribution | Tissue engineering applications: Cartilage lesions repair by the use of autologous chondrocytes |
|---|---|
| Original language | Italian |
| Pages (from-to) | 364-371 |
| Number of pages | 8 |
| Journal | Reumatismo |
| Volume | 54 |
| Issue number | 4 |
| Publication status | Published - 2002 |
ASJC Scopus subject areas
- Rheumatology