Abstract
Stem cells and regenerative medicine have obtained a remarkable consent from the scientific community for their promising ability to recover aged, injured and diseased tissue. However, despite the noteworthy potential, hurdles currently hinder their use and clinical application: cell survival, immune response, tissue engraftment and efficient differentiation. Hence a new interdisciplinary scientific approach, such as tissue engineering, is going deep attempts to mimic neo-tissue-genesis as well as stem cell engraftment amelioration. Skeletal muscle tissue engineering represents a great potentiality in medicine for muscle regeneration exploiting new generation injectable hydrogel as scaffold supporting progenitor/stem cells for muscle differentiation reconstructing the natural skeletal muscle tissue architecture influenced by matrix mechanical and physical property and by a dynamic environment.
| Original language | English |
|---|---|
| Pages (from-to) | 230-234 |
| Number of pages | 5 |
| Journal | Muscles, Ligaments and Tendons Journal |
| Volume | 2 |
| Issue number | 3 |
| Publication status | Published - Jul 2012 |
Keywords
- Hydrogel
- Mesoangioblast
- Skeletal muscle
- Stem cell
- Tissue engineering
ASJC Scopus subject areas
- Orthopedics and Sports Medicine