LA REAZIONE TESSUTALE AL SILICONE: VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI

Translated title of the contribution: Tissue reaction to silicon: Evaluation through experimental implants

A. Faga, L. Valdatta, A. Reho, S. Stea, M. E. Donati, A. Pizzoferrato

Research output: Contribution to journalArticle

Abstract

The authors reports their experience on implants of three different silicones: medical grade silicon elastomer, collagen-coated elastomer, and gel of silicon used for filling breast prosthesis. Materials were implanted in subcutaneous pocket of Sprague-Dawley rats; histocompatibility was assessed 7, 30 and 60 days after surgery. Peri-implant tissues were analyzed by means of immunohistochemical techniques to identify lymphocyte subpopulations and expression of interleukin 2 receptor. Image analysis led to a quantitative assessment. As a conclusion, the tested materials did not show acute local toxicity and induced the development of a fibrous tissue layer which, although differently extended, was always moderate. Silicon gel showed a remarkable tendency to spread out. Neither B nor T lymphocytes foci were demonstrated.

Translated title of the contributionTissue reaction to silicon: Evaluation through experimental implants
Original languageItalian
Pages (from-to)48-51
Number of pages4
JournalRivista Italiana di Chirurgia Plastica
Volume26
Issue number1 SUPPL.
Publication statusPublished - 1994

ASJC Scopus subject areas

  • Surgery

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    Faga, A., Valdatta, L., Reho, A., Stea, S., Donati, M. E., & Pizzoferrato, A. (1994). LA REAZIONE TESSUTALE AL SILICONE: VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI. Rivista Italiana di Chirurgia Plastica, 26(1 SUPPL.), 48-51.