LA REAZIONE TESSUTALE AL SILICONE: VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI

Translated title of the contribution: Tissue reaction to silicon: Evaluation through experimental implants

A. Faga, L. Valdatta, A. Reho, S. Stea, M. E. Donati, A. Pizzoferrato

Research output: Contribution to journalArticle

Abstract

The authors reports their experience on implants of three different silicones: medical grade silicon elastomer, collagen-coated elastomer, and gel of silicon used for filling breast prosthesis. Materials were implanted in subcutaneous pocket of Sprague-Dawley rats; histocompatibility was assessed 7, 30 and 60 days after surgery. Peri-implant tissues were analyzed by means of immunohistochemical techniques to identify lymphocyte subpopulations and expression of interleukin 2 receptor. Image analysis led to a quantitative assessment. As a conclusion, the tested materials did not show acute local toxicity and induced the development of a fibrous tissue layer which, although differently extended, was always moderate. Silicon gel showed a remarkable tendency to spread out. Neither B nor T lymphocytes foci were demonstrated.

Original languageItalian
Pages (from-to)48-51
Number of pages4
JournalRivista Italiana di Chirurgia Plastica
Volume26
Issue number1 SUPPL.
Publication statusPublished - 1994

Fingerprint

Experimental Implants
Silicon
Elastomers
Gels
Histocompatibility
Interleukin-2 Receptors
Lymphocyte Subsets
Silicones
Ambulatory Surgical Procedures
Prostheses and Implants
Sprague Dawley Rats
Breast
Collagen
T-Lymphocytes

ASJC Scopus subject areas

  • Surgery

Cite this

Faga, A., Valdatta, L., Reho, A., Stea, S., Donati, M. E., & Pizzoferrato, A. (1994). LA REAZIONE TESSUTALE AL SILICONE: VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI. Rivista Italiana di Chirurgia Plastica, 26(1 SUPPL.), 48-51.

LA REAZIONE TESSUTALE AL SILICONE : VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI. / Faga, A.; Valdatta, L.; Reho, A.; Stea, S.; Donati, M. E.; Pizzoferrato, A.

In: Rivista Italiana di Chirurgia Plastica, Vol. 26, No. 1 SUPPL., 1994, p. 48-51.

Research output: Contribution to journalArticle

Faga, A, Valdatta, L, Reho, A, Stea, S, Donati, ME & Pizzoferrato, A 1994, 'LA REAZIONE TESSUTALE AL SILICONE: VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI', Rivista Italiana di Chirurgia Plastica, vol. 26, no. 1 SUPPL., pp. 48-51.
Faga, A. ; Valdatta, L. ; Reho, A. ; Stea, S. ; Donati, M. E. ; Pizzoferrato, A. / LA REAZIONE TESSUTALE AL SILICONE : VALUTAZIONE MEDIANTE IMPIANTI SPERIMENTALI. In: Rivista Italiana di Chirurgia Plastica. 1994 ; Vol. 26, No. 1 SUPPL. pp. 48-51.
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