Titanium oxide antibacterial surfaces in biomedical devices

Livia Visai, Luigi de Nardo, Carlo Punta, Lucio Melone, Alberto Cigada, Marcello Imbriani, Carla Renata Arciola

Research output: Contribution to journalArticlepeer-review


Titanium oxide is a heterogeneous catalyst whose efficient photoinduced activity, related to some of its allotropic forms, paved the way for its widespread technological use. Here, we offer a comparative analysis of the use of titanium oxide as coating for materials in biomedical devices. First, we introduce the photoinduced catalytic mechanisms of TiO 2 and their action on biological environment and bacteria. Second, we overview the main physical and chemical technologies for structuring suitable TiO 2 coatings on biomedical devices. We then present the approaches for in vitro characterization of these surfaces. Finally, we discuss the main aspects of TiO 2 photoactivated antimicrobial activity on medical devices and limitations for these types of applications.

Original languageEnglish
Pages (from-to)929-946
Number of pages18
JournalInternational Journal of Artificial Organs
Issue number9
Publication statusPublished - Sep 2011


  • Antibacterial properties
  • Biomaterial surface modifications
  • Infectionresistant materials
  • Titanium oxide

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Bioengineering
  • Medicine (miscellaneous)


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