TMS in movement disorders

Alfredo Berardelli, Mark Hallett

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Transcranial magnetic stimulation (TMS) is applied to study patients with movement disorders. This article reviews the findings of such applications in patients with Parkinson's disease, dystonia, Huntington's disease, Tourette's syndrome, and essential tremor. The findings related to Parkinson's disease are characterized by a shortening of the cortical silence period (cSP), a reduction of short intracortical inhibition, an increase in the long-lasting intracortical inhibition, and a reduction of the normal motor evoked potential facilitation after single and repetitive TMS stimuli. Studies with paired-pulse TMS have provided controversial information on cortical motor excitability in Huntington's disease. The findings in dystonia include: a reduction of the short intracortical inhibition and a shortening of the cSP. In Tourette's syndrome patients, the cSP is short and intracortical inhibition is decreased. Patients with essential tremor have normal corticospinal conduction, normal duration of the cSP, and normal intracortical inhibition. Such application of TMS has produced enormous data and continues to do so.

Original languageEnglish
Title of host publicationOxford Handbook of Transcranial Stimulation
PublisherOxford University Press
ISBN (Print)9780191744013, 9780198568926
DOIs
Publication statusPublished - Nov 21 2012

Fingerprint

Transcranial Magnetic Stimulation
Movement Disorders
Essential Tremor
Tourette Syndrome
Dystonia
Huntington Disease
Parkinson Disease
Motor Evoked Potentials
Inhibition (Psychology)

Keywords

  • Dystonia
  • Essential tremor
  • Huntington's disease
  • Movement disorders
  • Parkinson's disease
  • Tourette's syndrome
  • Transcranial magnetic stimulation

ASJC Scopus subject areas

  • Psychology(all)

Cite this

Berardelli, A., & Hallett, M. (2012). TMS in movement disorders. In Oxford Handbook of Transcranial Stimulation Oxford University Press. https://doi.org/10.1093/oxfordhb/9780198568926.013.0021

TMS in movement disorders. / Berardelli, Alfredo; Hallett, Mark.

Oxford Handbook of Transcranial Stimulation. Oxford University Press, 2012.

Research output: Chapter in Book/Report/Conference proceedingChapter

Berardelli, A & Hallett, M 2012, TMS in movement disorders. in Oxford Handbook of Transcranial Stimulation. Oxford University Press. https://doi.org/10.1093/oxfordhb/9780198568926.013.0021
Berardelli A, Hallett M. TMS in movement disorders. In Oxford Handbook of Transcranial Stimulation. Oxford University Press. 2012 https://doi.org/10.1093/oxfordhb/9780198568926.013.0021
Berardelli, Alfredo ; Hallett, Mark. / TMS in movement disorders. Oxford Handbook of Transcranial Stimulation. Oxford University Press, 2012.
@inbook{3be48c183bc7416f8d095e908d61702d,
title = "TMS in movement disorders",
abstract = "Transcranial magnetic stimulation (TMS) is applied to study patients with movement disorders. This article reviews the findings of such applications in patients with Parkinson's disease, dystonia, Huntington's disease, Tourette's syndrome, and essential tremor. The findings related to Parkinson's disease are characterized by a shortening of the cortical silence period (cSP), a reduction of short intracortical inhibition, an increase in the long-lasting intracortical inhibition, and a reduction of the normal motor evoked potential facilitation after single and repetitive TMS stimuli. Studies with paired-pulse TMS have provided controversial information on cortical motor excitability in Huntington's disease. The findings in dystonia include: a reduction of the short intracortical inhibition and a shortening of the cSP. In Tourette's syndrome patients, the cSP is short and intracortical inhibition is decreased. Patients with essential tremor have normal corticospinal conduction, normal duration of the cSP, and normal intracortical inhibition. Such application of TMS has produced enormous data and continues to do so.",
keywords = "Dystonia, Essential tremor, Huntington's disease, Movement disorders, Parkinson's disease, Tourette's syndrome, Transcranial magnetic stimulation",
author = "Alfredo Berardelli and Mark Hallett",
year = "2012",
month = "11",
day = "21",
doi = "10.1093/oxfordhb/9780198568926.013.0021",
language = "English",
isbn = "9780191744013",
booktitle = "Oxford Handbook of Transcranial Stimulation",
publisher = "Oxford University Press",

}

TY - CHAP

T1 - TMS in movement disorders

AU - Berardelli, Alfredo

AU - Hallett, Mark

PY - 2012/11/21

Y1 - 2012/11/21

N2 - Transcranial magnetic stimulation (TMS) is applied to study patients with movement disorders. This article reviews the findings of such applications in patients with Parkinson's disease, dystonia, Huntington's disease, Tourette's syndrome, and essential tremor. The findings related to Parkinson's disease are characterized by a shortening of the cortical silence period (cSP), a reduction of short intracortical inhibition, an increase in the long-lasting intracortical inhibition, and a reduction of the normal motor evoked potential facilitation after single and repetitive TMS stimuli. Studies with paired-pulse TMS have provided controversial information on cortical motor excitability in Huntington's disease. The findings in dystonia include: a reduction of the short intracortical inhibition and a shortening of the cSP. In Tourette's syndrome patients, the cSP is short and intracortical inhibition is decreased. Patients with essential tremor have normal corticospinal conduction, normal duration of the cSP, and normal intracortical inhibition. Such application of TMS has produced enormous data and continues to do so.

AB - Transcranial magnetic stimulation (TMS) is applied to study patients with movement disorders. This article reviews the findings of such applications in patients with Parkinson's disease, dystonia, Huntington's disease, Tourette's syndrome, and essential tremor. The findings related to Parkinson's disease are characterized by a shortening of the cortical silence period (cSP), a reduction of short intracortical inhibition, an increase in the long-lasting intracortical inhibition, and a reduction of the normal motor evoked potential facilitation after single and repetitive TMS stimuli. Studies with paired-pulse TMS have provided controversial information on cortical motor excitability in Huntington's disease. The findings in dystonia include: a reduction of the short intracortical inhibition and a shortening of the cSP. In Tourette's syndrome patients, the cSP is short and intracortical inhibition is decreased. Patients with essential tremor have normal corticospinal conduction, normal duration of the cSP, and normal intracortical inhibition. Such application of TMS has produced enormous data and continues to do so.

KW - Dystonia

KW - Essential tremor

KW - Huntington's disease

KW - Movement disorders

KW - Parkinson's disease

KW - Tourette's syndrome

KW - Transcranial magnetic stimulation

UR - http://www.scopus.com/inward/record.url?scp=84923667103&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84923667103&partnerID=8YFLogxK

U2 - 10.1093/oxfordhb/9780198568926.013.0021

DO - 10.1093/oxfordhb/9780198568926.013.0021

M3 - Chapter

AN - SCOPUS:84923667103

SN - 9780191744013

SN - 9780198568926

BT - Oxford Handbook of Transcranial Stimulation

PB - Oxford University Press

ER -