Abstract
The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.
Translated title of the contribution | TNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii |
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Original language | Italian |
Pages (from-to) | 393-394 |
Number of pages | 2 |
Journal | Medicina - Rivista della Enciclopedia Medica Italiana |
Volume | 10 |
Issue number | 4 |
Publication status | Published - 1990 |
ASJC Scopus subject areas
- Medicine(all)