MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

E. Tamburrini; A. De Luca; G. Ventura; G. Maiuro; A. Siracusano; E. Ortona; A. Antinori

MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

Translated title of the contribution: TNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii

E. Tamburrini, A. De Luca, G. Ventura, G. Maiuro, A. Siracusano, E. Ortona, A. Antinori

Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani

Research output: Contribution to journal › Article › peer-review

Abstract

The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

Translated title of the contribution	TNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii
Original language	Italian
Pages (from-to)	393-394
Number of pages	2
Journal	Medicina - Rivista della Enciclopedia Medica Italiana
Volume	10
Issue number	4
Publication status	Published - 1990

ASJC Scopus subject areas

Medicine(all)

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MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE. / Tamburrini, E.; De Luca, A.; Ventura, G.; Maiuro, G.; Siracusano, A.; Ortona, E.; Antinori, A.

In: Medicina - Rivista della Enciclopedia Medica Italiana, Vol. 10, No. 4, 1990, p. 393-394.

Research output: Contribution to journal › Article › peer-review

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abstract = "The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.",

author = "E. Tamburrini and {De Luca}, A. and G. Ventura and G. Maiuro and A. Siracusano and E. Ortona and A. Antinori",

year = "1990",

language = "Italian",

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AU - Tamburrini, E.

AU - De Luca, A.

AU - Ventura, G.

AU - Maiuro, G.

AU - Siracusano, A.

AU - Ortona, E.

AU - Antinori, A.

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N2 - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

AB - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

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MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

Abstract

ASJC Scopus subject areas

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