MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

Translated title of the contribution: TNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii

E. Tamburrini, A. De Luca, G. Ventura, G. Maiuro, A. Siracusano, E. Ortona, A. Antinori

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

Original languageItalian
Pages (from-to)393-394
Number of pages2
JournalMedicina - Rivista della Enciclopedia Medica Italiana
Volume10
Issue number4
Publication statusPublished - 1990

Fingerprint

Pneumocystis carinii
Tumor Necrosis Factor-alpha
Macrophages
Pneumocystis Pneumonia
Endotoxins
Cysts
Monocytes
Steroids
In Vitro Techniques
Serum

ASJC Scopus subject areas

  • Medicine(all)

Cite this

MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE. / Tamburrini, E.; De Luca, A.; Ventura, G.; Maiuro, G.; Siracusano, A.; Ortona, E.; Antinori, A.

In: Medicina - Rivista della Enciclopedia Medica Italiana, Vol. 10, No. 4, 1990, p. 393-394.

Research output: Contribution to journalArticle

@article{9d9286b8301240988f2936771ab4bcb6,
title = "MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE",
abstract = "The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.",
author = "E. Tamburrini and {De Luca}, A. and G. Ventura and G. Maiuro and A. Siracusano and E. Ortona and A. Antinori",
year = "1990",
language = "Italian",
volume = "10",
pages = "393--394",
journal = "Medicina - Rivista della Enciclopedia Medica Italiana",
issn = "0392-6516",
number = "4",

}

TY - JOUR

T1 - MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

AU - Tamburrini, E.

AU - De Luca, A.

AU - Ventura, G.

AU - Maiuro, G.

AU - Siracusano, A.

AU - Ortona, E.

AU - Antinori, A.

PY - 1990

Y1 - 1990

N2 - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

AB - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

UR - http://www.scopus.com/inward/record.url?scp=0025534205&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025534205&partnerID=8YFLogxK

M3 - Articolo

VL - 10

SP - 393

EP - 394

JO - Medicina - Rivista della Enciclopedia Medica Italiana

JF - Medicina - Rivista della Enciclopedia Medica Italiana

SN - 0392-6516

IS - 4

ER -