MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE

Translated title of the contribution: TNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii

E. Tamburrini, A. De Luca, G. Ventura, G. Maiuro, A. Siracusano, E. Ortona, A. Antinori

Research output: Contribution to journalArticlepeer-review

Abstract

The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.

Translated title of the contributionTNF-alpha released in vitro by human macrophages after stimulus with murine Pneumocystis carinii
Original languageItalian
Pages (from-to)393-394
Number of pages2
JournalMedicina - Rivista della Enciclopedia Medica Italiana
Volume10
Issue number4
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Medicine(all)

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