Abstract
The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.
| Original language | Italian |
|---|---|
| Pages (from-to) | 393-394 |
| Number of pages | 2 |
| Journal | Medicina - Rivista della Enciclopedia Medica Italiana |
| Volume | 10 |
| Issue number | 4 |
| Publication status | Published - 1990 |
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ASJC Scopus subject areas
- Medicine(all)
Cite this
MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE. / Tamburrini, E.; De Luca, A.; Ventura, G.; Maiuro, G.; Siracusano, A.; Ortona, E.; Antinori, A.
In: Medicina - Rivista della Enciclopedia Medica Italiana, Vol. 10, No. 4, 1990, p. 393-394.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - MACROFAGI DI SOGGETTI ADULTI SANI RILASCIANO TNF-ALFA DOPO ESPOSIZIONE A PNEUMOCYSTIS CARINII DI ORIGINE MURINA. STUDIO PRELIMINARE
AU - Tamburrini, E.
AU - De Luca, A.
AU - Ventura, G.
AU - Maiuro, G.
AU - Siracusano, A.
AU - Ortona, E.
AU - Antinori, A.
PY - 1990
Y1 - 1990
N2 - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.
AB - The ability of Pneumocystis carinii to induce TNF-alpha release by macrophages from adult healthy humans was investigated. Monocytes and monocytes derived macrophages produced a high amount of TNF-alpha when exposed to P. carinii cysts obtained from rats with steroid induced pneumocystosis. TNF-alpha release was P. carinii specific as shown by the inhibition exerted by the anti-P. carinii hyperimmune serum and it was not mediated by putative traces of endotoxin.
UR - http://www.scopus.com/inward/record.url?scp=0025534205&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025534205&partnerID=8YFLogxK
M3 - Articolo
C2 - 2099981
AN - SCOPUS:0025534205
VL - 10
SP - 393
EP - 394
JO - Medicina - Rivista della Enciclopedia Medica Italiana
JF - Medicina - Rivista della Enciclopedia Medica Italiana
SN - 0392-6516
IS - 4
ER -