TNM independent prognostic factors in lung cancer

Kenji Kawamukai, Alfredo Cesario, Stefano Margaritora, Elisa Meacci, Alessio Piraino, Maria Letizia Vita, Adele Tessitore, Giacomo Cusumano, Pierluigi Granone

Research output: Contribution to journalArticlepeer-review


Large studies have demonstrated that TNM staging system is the most consistent prognostic factor in patients with non small cell lung carcinoma. However, because patients within the same stage may have very different survival, better prognostic information is needed. The recent progress in molecular biology has allowed the analysis of proteins and genes involved in cancer development. To date, more than 150 different prognostic factors affecting survival in patients with lung cancer have been discovered and extensively studied. Despite the encouraging prognostic results in angiogenesis markers, there is not yet a molecular marker validated in large prospective trials that has major independent predictive prognostic value.

Original languageEnglish
Pages (from-to)373-376
Number of pages4
JournalRays - International Journal of Radiological Sciences
Issue number4
Publication statusPublished - 2004


  • Lung cancer
  • Molecular markers
  • Prognostic factors

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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