Tolerance: Pregnancy matters

Franco Locatelli

Research output: Contribution to journal › Article

Abstract

In this issue of Blood, van Halteren and colleagues demonstrate that not only antigen-specific CD8 + CTLs, but also antigen-specific CD8 + T regs can emerge during pregnancy and persist over time when mother and offspring differ for minor histocompatibility antigens.1 The relative ratio between these 2 populations, either promoting aggression against allogeneic tissues or tumor cells or tolerance toward alloantigens, is of potential great relevance in the context of HSCT.

Original languageEnglish
Pages (from-to)2208-2209
Number of pages2
JournalBlood
Volume114
Issue number11
DOIs
Publication statusPublished - 2009

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CD8 Antigens
Antigens
Pregnancy
Histocompatibility
Isoantigens
Aggression
Tumors
Blood
Cells
Tissue
Population
Neoplasms

ASJC Scopus subject areas

  • Hematology
  • Biochemistry
  • Cell Biology
  • Immunology

Cite this

Tolerance : Pregnancy matters. / Locatelli, Franco.

In: Blood, Vol. 114, No. 11, 2009, p. 2208-2209.

Research output: Contribution to journal › Article

Locatelli, F 2009, 'Tolerance: Pregnancy matters', Blood, vol. 114, no. 11, pp. 2208-2209. https://doi.org/10.1182/blood-2009-06-228528
Locatelli F. Tolerance: Pregnancy matters. Blood. 2009;114(11):2208-2209. https://doi.org/10.1182/blood-2009-06-228528
Locatelli, Franco. / Tolerance : Pregnancy matters. In: Blood. 2009 ; Vol. 114, No. 11. pp. 2208-2209.
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