Abstract
In this issue of Blood, van Halteren and colleagues demonstrate that not only antigen-specific CD8 + CTLs, but also antigen-specific CD8 + T regs can emerge during pregnancy and persist over time when mother and offspring differ for minor histocompatibility antigens.1 The relative ratio between these 2 populations, either promoting aggression against allogeneic tissues or tumor cells or tolerance toward alloantigens, is of potential great relevance in the context of HSCT.
Original language | English |
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Pages (from-to) | 2208-2209 |
Number of pages | 2 |
Journal | Blood |
Volume | 114 |
Issue number | 11 |
DOIs | |
Publication status | Published - 2009 |
ASJC Scopus subject areas
- Hematology
- Biochemistry
- Cell Biology
- Immunology