Toll-like receptor 2 in serum: A potential diagnostic marker of prosthetic joint infection?

Emanuela Galliera, Lorenzo Drago, Christian Vassena, Carlo Romanò, Monica Gioia Marazzi, Lucia Salcito, Massimiliano M. Corsi Romanelli

Research output: Contribution to journalArticle

Abstract

Prosthetic joint infection (PJI) is a severe complication of arthroplasty and is still lacking diagnostic gold standards. PJI patients display high Toll-like receptor 2 (TLR2) serum levels, correlating with canonical inflammatory markers (C-reactive protein [CRP], interleukin 6 [IL-6], tumor necrosis factor alpha [TNF-α], and IL-1). Therefore, TLR2 serum levels could be considered a new potential diagnostic tool in the early detection of PJI.

Original languageEnglish
Pages (from-to)620-623
Number of pages4
JournalJournal of Clinical Microbiology
Volume52
Issue number2
DOIs
Publication statusPublished - Feb 2014

ASJC Scopus subject areas

  • Microbiology (medical)

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