Toll-like receptors

Research output: Contribution to journalArticle

58 Citations (Scopus)

Abstract

Toll-like receptors (TLRs) are a growing family of molecules involved in innate immunity. Accumulating evidence suggests that TLR molecules are involved in signalling receptor complexes which recognise components of Gram- positive and Gram-negative bacteria and mycobacteria. Differential expression and regulation as well as distinct though overlapping ligand recognition patterns may underlie the existence of a vast TLR family. Apparent structural and functional redundancy may render certain outputs of the TLR family robust. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

Original languageEnglish
Pages (from-to)251-255
Number of pages5
JournalMicrobes and Infection
Volume2
Issue number3
DOIs
Publication statusPublished - Mar 2000

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Toll-Like Receptors
Mycobacterium
Gram-Negative Bacteria
Innate Immunity
Ligands

Keywords

  • Inflammation
  • Interleukin-1
  • Lipopolysaccharide
  • Receptor
  • Toll

ASJC Scopus subject areas

  • Microbiology
  • Infectious Diseases

Cite this

Toll-like receptors. / Muzio, Marta; Mantovani, Alberto.

In: Microbes and Infection, Vol. 2, No. 3, 03.2000, p. 251-255.

Research output: Contribution to journalArticle

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