Tomographic imaging of the spleen: The role of morphological and metabolic features in differentiating benign from malignant diseases

Pier Paolo Mainenti, Delfina Iodice, Immacolata Cozzolino, Sabrina Segreto, Sergio Capece, Giacomo Sica, Mario Magliulo, Giuseppe Ciancia, Leonardo Pace, Marco Salvatore

Research output: Contribution to journalArticlepeer-review

Abstract

To evaluate the tomographic features in differentiating benign from malignant splenic diseases, 54 patients with a cytohistological examination and a contrast-enhanced multidetector computed tomography (ce-MDCT) and/or positron emission tomography/computed tomography (PET/CT) were retrospectively selected. Significant associations were observed between ce-MDCT Pattern 3 (focal hyperdense lesion) and Pattern 4 (infarcts/cysts) as well as PET/CT Pattern 3 (focal photopenia/diffuse uptakemax) as well as lesion characteristics was observed. The metabolic data do not improve the performance of morphological patterns.

Original languageEnglish
Pages (from-to)559-567
Number of pages9
JournalClinical Imaging
Volume36
Issue number5
DOIs
Publication statusPublished - Sep 2012

Keywords

  • Benign disease
  • CT
  • Malignant disease
  • PET/CT
  • Spleen

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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