Tomotherapy: When the patient is a child or an adolescent: hopes, results and issues

M. Mascarin, G. Franchin, M. Gigante, E. Minatel, A. Drigo, A. Dassie, G. Sartor, I. Abu Rumeileh, R. Innocente, M. Avanzo, C. Cappelletto, E. Capra, E. Borsatti, M. De Cicco, M. G. Trovò

Research output: Contribution to journalArticlepeer-review


SUMMARY: We describe our experience in 31 pediatric or adolescent oncological patients (median age 14 years old; range 2-24 years) treated with intensity modulation radiation therapy (IMRT) delivered with linear accelerator (11 patients) or tomotherapy (20 patients). Tomotherapy represents a significant advance in the ability to deliver the high radiation doses that appear to be required to improve the local control of several pediatric tumors. It demonstrated excellent target coverage, homogeneity and organ sparing compared with conventional radiotherapy. Possible disadvantages of tomotherapy in children are also discussed such as increased low dose to non-target tissue, prolonged treatment planning and set-up time, increased anesthesia time and increased overall integral dose.

Original languageEnglish
Pages (from-to)21-28
Number of pages8
JournalRivista Medica
Issue number3
Publication statusPublished - Sep 2007


  • Adolescent tumors
  • Brain tumors
  • Cranio-spinal irradiation
  • IMRT
  • Nasopharynx cancer
  • Pediatric tumors
  • Radiotherapy
  • Sarcoma
  • Tomotherapy
  • Whole abdominal irradiation

ASJC Scopus subject areas

  • Medicine(all)


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