Tonic cervical influences on eye nystagmus following hemilabyrinthectomy: immediate and plastic effects

Vito E. Pettorossi, Laura Petrosini

Research output: Contribution to journalArticle

Abstract

In intact guinea pigs a passive horizontal rotation of the body about the fixed head induces compensatory ocular movements (cervico-ocular reflex). When the static neck deviation is maintained, a significant ocular displacement is observed. In acutely hemilabyrinthectomized animals, static body deviation towards the lesion side tonically alters eyenystagmus. It affects slow phase eye velocity and quick phase amplitude and frequency causing the eye to reach a less eccentric orbital position. Apart from such immediate influences, a plastic effect on eye nystagmus abatement is induced. In the animals restrained with no body-on-head deviation, abatement of nystagmus is delayed with respect to the animals restrained with 35° body deviation towards the lesion side. Thus the head position signal is not only a contributing factor for the correction of postural deficits but also influences the time course of the ocular balancing process following unilateral vestibular damage.

Original languageEnglish
Pages (from-to)11-19
Number of pages9
JournalBrain Research
Volume324
Issue number1
DOIs
Publication statusPublished - Dec 17 1984

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Keywords

  • cervical afferents
  • cervico-ocular reflex
  • eye nystagmus
  • guinea pig
  • hemilabyrinthectomy
  • vestibular compensation

ASJC Scopus subject areas

  • Developmental Biology
  • Molecular Biology
  • Clinical Neurology
  • Neuroscience(all)

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