TOPEM: A PET-TOF endorectal probe, compatible with MRI for diagnosis and follow up of prostate cancer

F. Garibaldi, S. Capuani, S. Colilli, L. Cosentino, F. Cusanno, R. De Leo, P. Finocchiaro, M. Foresta, F. Giove, F. Giuliani, M. Gricia, F. Loddo, M. Lucentini, B. Maraviglia, F. Meddi, E. Monno, P. Musico, A. Pappalardo, R. Perrino, A. RanieriA. Rivetti, F. Santavenere, C. Tammad

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Prostate cancer is the most common disease in men and the second leading cause of cancer death. Generic large instruments for diagnosis have sensitivity, spatial resolution, and contrast inferior with respect to dedicated prostate imagers. Multimodality imaging can play a significant role merging anatomical and functional details coming from simultaneous PET and MRI. The TOPEM project has the goal of designing, building, and testing an endorectal PET-TOF MRI probe. The performance is dominated by the detector close to the source. Results from simulation show spatial resolution of ∼1.5 mm for source distances up to 80 mm. The efficiency is significantly improved with respect to the external PET. Mini-detectors have been built and tested. We obtained, for the first time, to our best knowledge, timing resolution of o400 ps and at the same time Depth Of Interaction (DOI) resolution of 1 mm or less.

Original languageEnglish
Pages (from-to)13-15
Number of pages3
JournalNuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment
Volume702
DOIs
Publication statusPublished - Feb 21 2013

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Magnetic resonance imaging
spatial resolution
cancer
Detectors
probes
detectors
Merging
Image sensors
death
time measurement
Imaging techniques
causes
sensitivity
Testing
simulation
interactions

Keywords

  • Endoscopic prob
  • Prostate cancer

ASJC Scopus subject areas

  • Instrumentation
  • Nuclear and High Energy Physics

Cite this

TOPEM : A PET-TOF endorectal probe, compatible with MRI for diagnosis and follow up of prostate cancer. / Garibaldi, F.; Capuani, S.; Colilli, S.; Cosentino, L.; Cusanno, F.; De Leo, R.; Finocchiaro, P.; Foresta, M.; Giove, F.; Giuliani, F.; Gricia, M.; Loddo, F.; Lucentini, M.; Maraviglia, B.; Meddi, F.; Monno, E.; Musico, P.; Pappalardo, A.; Perrino, R.; Ranieri, A.; Rivetti, A.; Santavenere, F.; Tammad, C.

In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, Vol. 702, 21.02.2013, p. 13-15.

Research output: Contribution to journalArticle

Garibaldi, F, Capuani, S, Colilli, S, Cosentino, L, Cusanno, F, De Leo, R, Finocchiaro, P, Foresta, M, Giove, F, Giuliani, F, Gricia, M, Loddo, F, Lucentini, M, Maraviglia, B, Meddi, F, Monno, E, Musico, P, Pappalardo, A, Perrino, R, Ranieri, A, Rivetti, A, Santavenere, F & Tammad, C 2013, 'TOPEM: A PET-TOF endorectal probe, compatible with MRI for diagnosis and follow up of prostate cancer', Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment, vol. 702, pp. 13-15. https://doi.org/10.1016/j.nima.2012.09.020
Garibaldi, F. ; Capuani, S. ; Colilli, S. ; Cosentino, L. ; Cusanno, F. ; De Leo, R. ; Finocchiaro, P. ; Foresta, M. ; Giove, F. ; Giuliani, F. ; Gricia, M. ; Loddo, F. ; Lucentini, M. ; Maraviglia, B. ; Meddi, F. ; Monno, E. ; Musico, P. ; Pappalardo, A. ; Perrino, R. ; Ranieri, A. ; Rivetti, A. ; Santavenere, F. ; Tammad, C. / TOPEM : A PET-TOF endorectal probe, compatible with MRI for diagnosis and follow up of prostate cancer. In: Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2013 ; Vol. 702. pp. 13-15.
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AU - Perrino, R.

AU - Ranieri, A.

AU - Rivetti, A.

AU - Santavenere, F.

AU - Tammad, C.

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