Topical chemotherapy for ocular surface squamous neoplasia: Current status

Ricardo Sepulveda, Jacob Pe'er, Edoardo Midena, Stefan Seregard, Harminder S. Dua, Arun D. Singh

Research output: Contribution to journalArticlepeer-review


Although there are no randomised trials directly comparing topical chemotherapeutic agents mitomycin-C, 5-fluorouracil, and interferon-α2b, published studies indicate equal efficacy of these agents for treatment of non-invasive ocular surface squamous neoplasia (80%-88%). 5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient.

Original languageEnglish
Pages (from-to)532-535
Number of pages4
JournalBritish Journal of Ophthalmology
Issue number5
Publication statusPublished - 2010

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience


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